Gene: TP53 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE The study concludes that rfhSP-D induces apoptosis in prostate tumor explants as well as in androgen dependent and independent prostate cancer cells via p53 and pAkt pathways. 31355132 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group CTD_human Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations. 29295717 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group CTD_human The long tail of oncogenic drivers in prostate cancer. 29610475 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE These findings suggest that EAF2 and p53 functionally interact in prostate tumor suppression and that simultaneous inactivation of EAF2 and p53 can drive prostate carcinogenesis. 29029019 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE Loss of Skp2 resulted in a striking decrease of Ezh2 levels in Pten/Trp53 double-null MEFs and in prostate tumors of Pten/Trp53 double-null mutant mice. 27869166 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE Importantly, we find that pharmacological inhibition of γ-secretase promotes growth arrest in both Pten-null and Pten/Trp53-null prostate tumours by triggering cellular senescence. 27941799 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 AlteredExpression group BEFREE Expressions of CD24 and mutant p53 were more frequently observed in late-stage and metastatic prostate tumors. 26712693 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group CTD_human Spatial genomic heterogeneity within localized, multifocal prostate cancer. 26005866 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group CTD_human Integrative molecular profiling of routine clinical prostate cancer specimens. 25735316 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE Met was amplified in 67% of prostate tumors from Pten p53 prostate conditional null mice and in approximately 30% of metastatic human prostate cancer specimens, often in association with loss of PTEN and TP53. 25381262 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE Murine double minute 2 siRNA and wild-type p53 gene therapy interact positively with zinc on prostate tumours in vitro and in vivo. 24447832 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE Targeted deletion of the signaling domain of β4 inhibited prostate tumor growth and progression in response to loss of p53 and Rb function in a mouse model of prostate cancer (PB-TAg mice). 23348745 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 AlteredExpression group BEFREE Analysis of prostate tumors has shown a direct expression correlation between sGCα1 and p53. 22174378 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE A subset of 64 prostate tumors was stained immunohistochemically for P53. 21778786 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 AlteredExpression group BEFREE We demonstrated that human prostate tumors had increased expression of MDM2 and mutant p53 proteins. 21444629 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group CTD_human A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. 21946351 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group CTD_human Association between polymorphisms of TP53 and MDM2 and prostate cancer risk in southern Chinese. 20875869 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 Biomarker group BEFREE Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor-initiating cells. 20124455 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 GeneticVariation group LHGDN Our aim was to determine the frequency of KLF6 and TP53 mutations in a well-defined group of prostate tumors with different stages and Gleason grades. 19020536 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 GeneticVariation group LHGDN Clinical significance of p53 alterations in surgically treated prostate cancers. 18552821 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 GeneticVariation group BEFREE Our aim was to determine the frequency of KLF6 and TP53 mutations in a well-defined group of prostate tumors with different stages and Gleason grades. 19020536 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 GeneticVariation group LHGDN TP53 mutation in prostate needle biopsies--comparison with patients follow-up. 18225585 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 GeneticVariation group LHGDN Paclitaxel enhanced radiation sensitization for the suppression of human prostate cancer tumor growth via a p53 independent pathway. 17823933 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 AlteredExpression group LHGDN Theaflavins induced apoptosis of LNCaP cells is mediated through induction of p53, down-regulation of NF-kappa B and mitogen-activated protein kinases pathways. 17499812 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.400 AlteredExpression group LHGDN Expression of androgen receptor is negatively regulated by p53. 18084622 2007