Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 GeneticVariation disease GWASCAT Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. 25574825 2015
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 GeneticVariation disease GWASDB Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594 2012
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 Biomarker disease BEFREE Here, we report that RNF114, previously identified as a psoriasis susceptibility gene, plays a regulatory role in the RANKL/RANK/TRAF6 signaling pathway that mediates osteoclastogenesis. 28708287 2018
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 GeneticVariation disease BEFREE ZNF313 and IL-13 are associated with risk for psoriasis in a Chinese Uygur population, and there is an effect of interaction between the two genes on this risk. 23617596 2013
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 GeneticVariation disease BEFREE After our first psoriasis genome-wide association study, we designed a custom genotyping array to fine-map eight genome-wide significant susceptibility loci known at that time (IL23R, IL13, IL12B, TNIP1, MHC, TNFAIP3, IL23A and RNF114) enabling genotyping of 2269 single-nucleotide polymorphisms (SNPs) in the eight loci for 2699 psoriasis cases and 2107 unaffected controls of European ancestry. 25182136 2015
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 GeneticVariation disease BEFREE The really interesting new gene (RING) finger protein 114 (RNF114) was originally identified as a psoriasis susceptibility gene broadly expressed in human tissues. 28625874 2017
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 Biomarker disease CTD_human A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190 2010
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 GeneticVariation disease GWASCAT Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594 2012
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 Biomarker disease BEFREE Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. 18364390 2008
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 GeneticVariation disease BEFREE A GWAS carried out by our group also identified RNF114, a gene encoding a novel ubiquitin binding protein, as a determinant for psoriasis susceptibility. 21571784 2011
Entrez Id: 55905
Gene Symbol: RNF114
RNF114
0.470 Biomarker disease BEFREE RNF114 [RING (really interesting new gene) finger protein 114] has been shown to be a novel psoriasis susceptibility gene, with a putative role in the regulation of immune responses, though the underlying mechanism was not fully identified. 24631332 2014