Gene: IL6 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 AlteredExpression group BEFREE Blood IL-6 levels were significantly higher (SMD = 0.31, 95% CI 0.02-0.59, p = 0.04) and blood IL-1β levels were significantly lower (SMD = -0.66, 95% CI -1.27 to -0.05, p = 0.05) in subjects at high-risk for psychosis versus controls. 30967316 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 AlteredExpression group BEFREE In the psychosis group, levels of IL-6 correlated positively with IgA anti-LPS antibodies and negatively correlated with vitamin D. 30414721 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 AlteredExpression group BEFREE Mean levels of IL6 (g = 0.62), TNFα (g = 0.56), interferon-γ (IFNγ) (g = 0.32), transforming growth factor-β (g = 0.53), and interleukin-17 (IL17) (g = 0.48) were elevated in psychosis. 30407606 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 Biomarker group BEFREE The goal of our study was to detect the serum concentrations of tumor necrosis factor (TNF)-α, interleukin (IL)-18, and IL-6 concentrations in patients with chronic schizophrenia in the acute relapse state at admission and at discharge and to analyze the correlations between the three cytokine concentrations with psychosis symptoms. 30782515 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 AlteredExpression group BEFREE Both baseline C-reactive protein (CRP) and Interleukin-6 levels were not shown to discriminate between converters and non-converters to psychosis. 29703661 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 Biomarker group BEFREE Previously reported associations between IL-6, depression and psychosis are unlikely to be fully explained by confounding. 29197507 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 GeneticVariation group BEFREE IL-6 in childhood were associated with subsequent risk of depression or psychotic disorders in early adulthood and in a dose dependent manner. 30439824 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 AlteredExpression group BEFREE Both hsCRP and IL-6 levels were associated with insidious psychosis onset, duration of illness and chronic schizophrenia course with deterioration. 25214388 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.090 AlteredExpression group BEFREE In subjects not taking cannabis, we found that patients diagnosed with ARMS or PD exhibited increased IL-6 levels when compared with HC (p=0.004). 24495605 2014