Gene: ITGB6 ×
Source: BEFREE ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3694
Gene Symbol: ITGB6
ITGB6 		0.330 Biomarker disease BEFREE A mutated pig phenotype characterized by age-related lung emphysema and resembling the ITGB6-/- mouse has been described previously. 24043489 2013
Entrez Id: 3694
Gene Symbol: ITGB6
ITGB6 		0.330 GeneticVariation disease BEFREE The deletion region of 2q24.2 includes the integrin beta6 gene (ITGB6), which may prevent acute lung injury and pulmonary emphysema. 20358620 2010
Entrez Id: 3694
Gene Symbol: ITGB6
ITGB6 		0.330 Biomarker disease BEFREE Here we report that Itgb6-null mice develop age-related emphysema that is completely abrogated either by transgenic expression of versions of the beta6 integrin subunit that support TGF-beta activation, or by the loss of Mmp12. 12634787 2003