×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
MEFV variants in exon 10 may affect clinical presentation of HSP in populations where FMF is common.
30513227
2019
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
Blood for MEFV gene mutation analysis was obtained either at the time of the Henoch-Schönlein purpura diagnosis or during follow-up visits.
30826945
2019
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
The association between MEFV gene polymorphisms and Henoch-Schönlein purpura , and additional SNP-SNP interactions in Chinese Han children.
27796522
2017
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
In addition, MEFV , whose mutations cause familial Mediterranean fever, could be an important candidate gene for HSP .
23325094
2013
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
However, it seems that MEFV gene mutations may not have any effect on the clinical presentation of HSP .
22451026
2013
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
In the present study, the mutation rate of the MEFV gene in HSP and its association with the clinical course of the disease were evaluated.
23981758
2013
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
MEFV mutations are more frequent in HSP than in the general population, and mutation carriers may have more severe clinical findings with higher inflammatory response, suggesting a dysregulation of the inflammatory response because of defective gene encoding the protein pyrine.
21231959
2011
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
Our results suggest that MEFV E148Q could be a contributory genetic factor to HSP and HSP -related joint syndromes.
20602240
2010
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
Biomarker
disease
BEFREE
Among the most interesting genes clearly associated with vasculitis, however, are uncommon alleles that also cause monogenic recessive diseases: MEFV in Behçet's disease and Henoch-Schönlein purpura , and A1AT in Wegener's granulomatosis.
20051862
2010
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
MEFV mutations modify the clinical presentation of Henoch-Schönlein purpura .
18843775
2008
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.100
GeneticVariation
disease
BEFREE
Prevalence and significance of mutations in the familial Mediterranean fever gene in Henoch-Schönlein purpura .
14615741
2003