|
HSP90B2P
|
0.100 |
Biomarker
|
disease |
BEFREE |
None of these modifications were observed, when another small HSP (HSPB1), also expressed in MCF-7 cells, was downregulated.
|
28060751 |
2017 |
|
HSP90B2P
|
0.100 |
Biomarker
|
disease |
BEFREE |
KIF5A mutations have been associated with a wide clinical spectrum, ranging from pure HSP to isolated peripheral nerve involvement or complicated HSP phenotypes.
|
26403765 |
2015 |
|
HSP90B2P
|
0.100 |
Biomarker
|
disease |
BEFREE |
In conclusion, our study provides evidence for the existence of molecular mimicry between cytokeratin-10 of keratin (host protein) and 65kDa HSP (groEL2) of M. leprae.
|
23121977 |
2013 |
|
HSP90B2P
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Mutations in the 23 known autosomal recessive HSP genes explain less than half of autosomal recessive HSP cases.
|
23486545 |
2013 |
|
HSP90B2P
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results directly implicate a reticulon protein in axonopathy, show that this protein participates in a network of interactions among HSP proteins involved in ER shaping, and further support the hypothesis that abnormal ER morphogenesis is a pathogenic mechanism in HSP.
|
22232211 |
2012 |
|
HSP90B2P
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We sequenced all exons of REEP1 and searched for rearrangements by multiplex ligation-dependent probe amplification (MLPA) in a large panel of 175 unrelated HSP index patients from kindreds with dominant inheritance (AD-HSP), with either pure (n = 102) or complicated (n = 73) forms of the disease, after exclusion of other known HSP genes.
|
21618648 |
2011 |
|
HSP90B2P
|
0.100 |
Biomarker
|
disease |
BEFREE |
HSP-6 (hsp70F) is a nematode orthologue of mthsp70.
|
17189267 |
2007 |
|
HSP90B2P
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The clinical similarities between Hereditary Spastic Paraplegia (HSP) and progressive MS, along with their analogous profiles of axonal loss in the long tracts, make the genes known to cause HSP biologically relevant candidates for the study of clinical outcome in MS. A cohort of sporadic MS cases and a set of unaffected controls were used to determine the role of HSP genes on MS susceptibility and disease severity.
|
17420921 |
2007 |
|
HSP90B2P
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We reviewed the literature for HSP with thin CC and found 113 HSP patients with thin CC previously described (35 with linkage to chromosome 15q13-15).
|
16102895 |
2006 |
|
HSP90B2P
|
0.100 |
Biomarker
|
disease |
BEFREE |
Prenatal genetic testing in HSP is possible for some individuals with the increasing availability of HSP gene analysis.
|
16469273 |
2006 |
|
HSP90B2P
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
No mutations of any of the other HSP genes tested were found in 15 patients with sporadic pure HSP who did not have mutations in the SPG4 gene.
|
16682546 |
2006 |