Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10159
Gene Symbol: ATP6AP2
ATP6AP2
0.010 Biomarker disease BEFREE (Pro)renin receptor may contribute to the generation of arterial angiotensin II in kidney failure patients. 19641301 2009
Entrez Id: 183
Gene Symbol: AGT
AGT
0.380 Biomarker disease BEFREE (Pro)renin receptor may contribute to the generation of arterial angiotensin II in kidney failure patients. 19641301 2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.020 AlteredExpression disease BEFREE 1,25-Dihydroxyvitamin D downregulation of TGFalpha/EGFR expression and growth signaling: a mechanism for the antiproliferative actions of the sterol in parathyroid hyperplasia of renal failure. 15225829 2004
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
0.020 Biomarker disease BEFREE 4-HNE-modified ankyrin have been described in diseases such as diabetes, renal failure, G6PD deficient, sickle cell trait and P. falciparum infected erythrocytes with different AB0 blood groups. 31804821 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.100 GeneticVariation disease BEFREE Renal failure after clinical heart transplantation is associated with the TGF-beta 1 codon 10 gene polymorphism. 11008076 2000
Entrez Id: 182
Gene Symbol: JAG1
JAG1
0.010 GeneticVariation disease BEFREE Renal failure and hypertension in Alagille syndrome with a novel JAG1 mutation. 16013021 2005
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.020 Biomarker disease BEFREE Renal failure causes early death of bcl-2 deficient mice. 16620920 2006
Entrez Id: 3075
Gene Symbol: CFH
CFH
0.040 Biomarker disease BEFREE Renal failure is a predominant complication of both Stx-HUS and atypical HUS, whereas neurological complications are more prominent in TTP. 16760911 2006
Entrez Id: 4627
Gene Symbol: MYH9
MYH9
0.380 GeneticVariation disease BEFREE Renal failure susceptibility genes identified by these methods, such as MYH9, have yielded novel insights into the pathogenesis of CKD. 21071974 2011
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.080 Biomarker disease BEFREE Kidney failure type was determined blinded to NGAL measurements. 22562534 2012
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
0.010 Biomarker disease BEFREE Renal failure activates Egr-1 in human and mouse tubular cells. 26960759 2016
Entrez Id: 84735
Gene Symbol: CNDP1
CNDP1
0.030 GeneticVariation disease BEFREE Renal failure progression was independent of CNDP1 genotype in the total cohort of CKD children. 27278783 2016
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
0.010 Biomarker disease BEFREE ESRD-free survival with proteinase 3 (PR3) versus myeloperoxidase- (MPO-) ANCA positivity stratified into 4 histological classes was investigated. 29854025 2018
Entrez Id: 4353
Gene Symbol: MPO
MPO
0.080 Biomarker disease BEFREE ESRD-free survival with proteinase 3 (PR3) versus myeloperoxidase- (MPO-) ANCA positivity stratified into 4 histological classes was investigated. 29854025 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.330 Biomarker disease BEFREE ESRD was also associated with a shift in MAIT PMA-induced cytokine production away from IFNγ production and toward granulocyte macrophage-colony stimulating factor (GM-CSF) secretion, and a loss of <i>E. coli</i>-stimulated tumor necrosis factor α expression. 29868028 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.010 Biomarker disease BEFREE ESRD was also associated with a shift in MAIT PMA-induced cytokine production away from IFNγ production and toward granulocyte macrophage-colony stimulating factor (GM-CSF) secretion, and a loss of <i>E. coli</i>-stimulated tumor necrosis factor α expression. 29868028 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.030 Biomarker disease BEFREE Renal failure in COPD can be unrecognized since elderly and frail patients may have normal serum creatinine concentration. 30523563 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.020 Biomarker disease BEFREE Bcl-2 is crucial for normal development in the kidney, with a deficiency in Bcl-2 producing such malformation that renal failure and death result. 10361261 1999
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.400 Biomarker disease BEFREE ACE or AT1R, may affect the progression to renal failure of patients (especially females) with NIDDM. 10364706 1999
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.020 Biomarker disease BEFREE VEGF plays also a critical role in kidney development, and its inactivation during early postnatal life results in the suppression of glomerular development and kidney failure. 10469350 1999
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.050 Biomarker disease BEFREE Lipoprotein(a) serum concentrations and apolipoprotein(a) phenotypes in mild and moderate renal failure. 10616846 2000
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.100 Biomarker disease BEFREE TGF-beta1-induced glomerular disorder is associated with impaired concentrating ability mimicking primary glomerular disease with renal failure in man. 11140698 2000
Entrez Id: 183
Gene Symbol: AGT
AGT
0.380 GeneticVariation disease BEFREE Angiotensinogen and angiotensin II type 1 receptor gene polymorphism in patients with autosomal dominant polycystic kidney disease: effect on hypertension and ESRD. 12950120 2003
Entrez Id: 23607
Gene Symbol: CD2AP
CD2AP
0.070 Biomarker disease BEFREE CD2AP knockout (-/-) mice develop a congenital nephrotic syndrome with podocyte foot-process effacements and die at 6 weeks of age from renal failure. 14643126 2003
Entrez Id: 4627
Gene Symbol: MYH9
MYH9
0.380 Biomarker disease BEFREE Nonmuscle myosin heavy chain II-A is responsible for MYH9-related disease, which is characterized by macrothrombocytopenia, granulocyte inclusions, deafness, cataracts, and renal failure. 15177565 2004