Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 834
Gene Symbol: CASP1
CASP1
0.020 AlteredExpression group BEFREE Also, HEK-293 cells expressing low levels of pro-caspase-1 exhibit decreased IL-1β expression and delayed OPN expression in response to RSV infection. 29677209 2018
Entrez Id: 834
Gene Symbol: CASP1
CASP1
0.020 Biomarker group BEFREE Thus, our studies have underscored the requirement of TLR2/MyD88/NF-κB pathway (first signal) and ROS/potassium efflux (second signal) for NLRP3/ASC inflammasome formation, leading to caspase-1 activation and subsequent IL-1β release during RSV infection. 22295065 2012