| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | group | BEFREE | Our recent data demonstrate that immunoproteasome catalytic subunit β2i contributes to angiotensin II (Ang II)-induced retinopathy in mice. | 31636038 | 2020 | ||||
|
0.080 | Biomarker | group | BEFREE | The localization of RAAS components within the retina has led to studies investigating the roles of angiotensin II, aldosterone and the counter regulatory arm of the pathway in vision-threatening retinopathies. | 31425690 | 2019 | ||||
|
0.080 | Biomarker | group | BEFREE | The immunoproteasome plays a critical role in controlling inflammatory responses, but whether activation of immunoproteasome contributes to angiotensin II (Ang II)-induced retinopathy remains unclear. | 29499566 | 2018 | ||||
|
0.080 | GeneticVariation | group | BEFREE | The ACE and AGT gene polymorphisms are not associated with the progress of diabetes developing into retinopathy in Chinese patients with type 2 diabetes. | 29378484 | 2018 | ||||
|
0.080 | Biomarker | group | BEFREE | The objective of this study was to evaluate the effects of irbesartan, an angiotensin II receptor antagonist, on IAP in adolescents and young adults with type 1 diabetes and early signs of retinopathy and nephropathy. | 15983321 | 2005 | ||||
|
0.080 | GeneticVariation | group | BEFREE | The AGT polymorphism did not have an additive effect on the association between ACE polymorphism and the development of diabetic nephropathy in patients with or without retinopathy. | 10499884 | 1999 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Angiotensin I-converting enzyme and angiotensinogen gene polymorphisms in non-insulin-dependent diabetes mellitus. Lack of relationship with diabetic nephropathy and retinopathy in a Caucasian Mediterranean population. | 9258285 | 1997 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Association with the I/D polymorphism of the ACE gene and M235T variant of the angiotensinogen gene (AGT) with microalbuminuria and retinopathy was examined. | 8587251 | 1995 |