|
HLA-DPB1
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
We have previously demonstrated that in our series HLADRB1* 03:01 and haplotype HLA-DRB1*04:01-DPB1*04:01 are associated with good prognosis sarcoidosis.
|
29229112 |
2017 |
|
HLA-DPB1
|
0.390 |
Biomarker
|
disease |
BEFREE |
No increase in sarcoidosis was seen with either Glu69 or beryllium exposure (none, <10, ≥10 years) as main effects: longer duration in possible beryllium jobs was related to COPD.
|
25305207 |
2015 |
|
HLA-DPB1
|
0.390 |
Biomarker
|
disease |
CTD_human |
Impact of negatively charged patches on the surface of MHC class II antigen-presenting proteins on risk of chronic beryllium disease.
|
17956852 |
2008 |
|
HLA-DPB1
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Initially, we studied the association of sarcoidosis with DQB1, and in the present study, we evaluated all amino acid variants of the HLA-DPB1, -DQB1, -DRB1, -DRB3, -DRB4 and -DRB5 genes to identify possible polymorphisms associated with the disease.
|
17559577 |
2007 |
|
HLA-DPB1
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
The HLA-DPB1 locus also contributed to susceptibility for sarcoidosis and, in contrast to chronic beryllium disease, a non-E(69)-containing allele, HLA-DPB1*0101, conveyed most of the risk.
|
14508706 |
2003 |
|
HLA-DPB1
|
0.390 |
Biomarker
|
disease |
CTD_human |
HLA-DRB1*1101: a significant risk factor for sarcoidosis in blacks and whites.
|
14508706 |
2003 |
|
HLA-DPB1
|
0.390 |
Biomarker
|
disease |
BEFREE |
These results suggest associations at the TAP loci occur independently of HLA-DPB1 associations, that TAP associations seen may be involved in determining sarcoidosis susceptibility, and that such susceptibilities differ between UK and Polish populations.
|
10471632 |
1999 |
|
HLA-DPB1
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
HLA-DQB1 and HLA-DPB1 genotypes in familial sarcoidosis.
|
9659531 |
1998 |
|
HLA-DPB1
|
0.390 |
Biomarker
|
disease |
BEFREE |
These results suggest that although HLA-DPB1 Glu69 is not associated with sarcoidosis, other alleles may make some contribution to susceptibility to sarcoidosis in African-Americans.
|
9655715 |
1998 |
|
HLA-DPB1
|
0.390 |
Biomarker
|
disease |
CTD_human |
HLA-DPB polymorphisms: Glu 69 association with sarcoidosis.
|
8909942 |
1996 |
|
HLA-DPB1
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
The aims of the present study were to attempt to define MHC class II alleles associated with sarcoidosis by comparison of their frequency in two groups of subjects and to compare the frequency of HLA-DPB1 Glu 69+/- and Glu 55+/-alleles in the same subjects.
|
8909942 |
1996 |
|
HLA-DPB1
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
To investigate whether the class I antigen-processing genes, encoded within the MHC class II region between the HLA-DP and -DQ loci, are involved in determining the susceptibility to sarcoidosis, TAP1, TAP2, and LMP2 alleles were analyzed by the PCR-RFLP method in 85 Japanese patients with sarcoidosis and 91 healthy controls.
|
8882407 |
1996 |