Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | We conclude that proangiogenic VEGF, and profibrotic FGF-2 and PDGF-AB may contribute to the progression of sarcoidosis, whereas TGF-β1, with its dual anti-inflammatory and profibrotic actions, may play a dichotomous protective or deleterious role. | 29679363 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Malondialdehyde and VEGF serum levels were obtained in all sarcoidosis patients and control subjects. | 28506681 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | These findings were in line with previous data on the role of HIF-1A/VEGF/ING-4 axis in the pathogenesis of sarcoidosis. | 26022899 | 2015 | ||||
|
0.070 | Biomarker | disease | BEFREE | In this study, we examined whether haplotypes of vascular endothelial growth factor (VEGF) and its receptors VEGFR-1 and VEGFR-2 are associated with the onset or the course of sarcoidosis. | 19741061 | 2010 | ||||
|
0.070 | GeneticVariation | disease | LHGDN | Vascular endothelial growth factor gene polymorphisms in Turkish patients with sarcoidosis. | 18554246 | 2008 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Our results suggest that increase in rarer T allele at + 813 locus of VEGF gene may diminish susceptibility to sarcoidosis in Turkish population. | 18554246 | 2008 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | We examined polymorphisms of the VEGF gene in 103 Japanese patients with sarcoidosis and 146 healthy Japanese control subjects. | 12740269 | 2003 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Since activated macrophages and monocytes are known to be involved in sarcoid granuloma formation in sarcoidosis, we investigated the expression of VEGF and its receptor flt in 33 paraffin-embedded lung tissue biopsies of patients with pulmonary sarcoidosis. | 9463589 | 1998 |