Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.360 GeneticVariation disease BEFREE These studies investigated the BDNF Val66Met variant and antipsychotic response in patients with SCZ or schizoaffective disorder. 30181602 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.360 AlteredExpression disease BEFREE In this context, we propose a longitudinal study of a cohort of SCZ and schizophrenic and schizoaffective disorder (SAD) Sardinian patients with the aim of disentangling the relationship between peripheral BDNF serum levels and changes of psychopathology, cognition and drug treatments. 28550022 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.360 GeneticVariation disease BEFREE We tested the hypothesis that a common functional variant in brain-derived neurotrophic factor (BDNF), Val66Met, which has been shown to be associated with increased body mass index (BMI) in schizophrenia (SCZ) and schizoaffective disorder (SAD), is also associated with antipsychotic-induced weight gain in bipolar disorder (BPD). 25874530 2015
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.360 GeneticVariation disease BEFREE Molecular genetic studies point to potential risk loci of psychotic depression shared with schizoaffective disorder (1q42, 22q11, 19p13), depression, bipolar disorder, and schizophrenia (6p, 8p22, 10p13-12, 10p14, 13q13-14, 13q32, 18p, 22q11-13) and several vulnerability genes possibly contributing to an increased risk of psychotic symptoms in depression (eg, BDNF, DBH, DTNBP1, DRD2, DRD4, GSK-3beta, MAO-A). 23512949 2013
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.360 GeneticVariation disease BEFREE Individuals with schizoaffective disorder and other affective disorders were significantly more likely to carry two copies of the most common BDNF haplotype (containing the valine allele of the Val66Met polymorphism) compared with healthy volunteers. 19336781 2009
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.360 Biomarker disease BEFREE BDNF genotyping was performed using polymerase chain reaction and pyrosequencing techniques in 96 patients with schizophrenia or schizoaffective disorder and 104 healthy control participants. 18628679 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.360 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004