Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64132
Gene Symbol: XYLT2
XYLT2
0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 2355
Gene Symbol: FOSL2
FOSL2
0.300 Biomarker disease MGD
Entrez Id: 2313
Gene Symbol: FLI1
FLI1
0.300 Biomarker disease MGD
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.250 Biomarker disease MGD
Entrez Id: 5053
Gene Symbol: PAH
PAH
0.170 Biomarker disease HPO
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
0.120 Biomarker disease HPO
Entrez Id: 7486
Gene Symbol: WRN
WRN
0.110 Biomarker disease HPO
Entrez Id: 3930
Gene Symbol: LBR
LBR
0.110 Biomarker disease HPO
Entrez Id: 7389
Gene Symbol: UROD
UROD
0.100 Biomarker disease HPO
Entrez Id: 23592
Gene Symbol: LEMD3
LEMD3
0.100 Biomarker disease HPO
Entrez Id: 5424
Gene Symbol: POLD1
POLD1
0.100 Biomarker disease HPO
Entrez Id: 6559
Gene Symbol: SLC12A3
SLC12A3
0.100 Biomarker disease HPO
Entrez Id: 1188
Gene Symbol: CLCNKB
CLCNKB
0.100 Biomarker disease HPO
Entrez Id: 7390
Gene Symbol: UROS
UROS
0.100 Biomarker disease HPO
Entrez Id: 3077
Gene Symbol: HFE
HFE
0.100 Biomarker disease HPO
Entrez Id: 55315
Gene Symbol: SLC29A3
SLC29A3
0.100 Biomarker disease HPO
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
0.400 GeneticVariation disease BEFREE These data suggest that genetic predisposition to the antitopo I response in PSS is associated most closely with the HLA-DQB1 locus. 1326003 1992
Entrez Id: 1060
Gene Symbol: CENPC
CENPC
0.020 Biomarker disease BEFREE CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate. 1339310 1992
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.090 Biomarker disease BEFREE These observations suggest that the complex interactions of beta 1 and beta 2 integrins, as well as ELAM-1 and ICAM-1, may be intimately involved in the pathogenesis of SSc, perhaps by mediating the homing and targeting of pathogenetic lymphocytes to the affected tissues. 1371389 1992
Entrez Id: 6401
Gene Symbol: SELE
SELE
0.040 Biomarker disease BEFREE These observations suggest that the complex interactions of beta 1 and beta 2 integrins, as well as ELAM-1 and ICAM-1, may be intimately involved in the pathogenesis of SSc, perhaps by mediating the homing and targeting of pathogenetic lymphocytes to the affected tissues. 1371389 1992
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.100 Biomarker disease BEFREE It is suggested that SSc fibroblasts are more sensitive to IL-1, and that the signal transduction of IL-1 through IL-1R may be eventually involved in the fibrosis of SSc. 1375465 1992
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.100 Biomarker disease BEFREE It is suggested that SSc fibroblasts are more sensitive to IL-1, and that the signal transduction of IL-1 through IL-1R may be eventually involved in the fibrosis of SSc. 1375465 1992
Entrez Id: 3554
Gene Symbol: IL1R1
IL1R1
0.020 AlteredExpression disease BEFREE Increased interleukin 1 receptor, type I, at messenger RNA and protein level in skin fibroblasts from patients with systemic sclerosis. 1375465 1992
Entrez Id: 26039
Gene Symbol: SS18L1
SS18L1
0.100 Biomarker disease BEFREE Serum from a CREST (Scleroderma syndrome) patient presenting a high titer of anticentromeric antibodies was chosen on the basis of specificity of labeling of cells on slides. 1378781 1992
Entrez Id: 780904
Gene Symbol: PSS
PSS
0.040 Biomarker disease BEFREE Scleroderma (progressive systemic sclerosis; PSS) is a connective tissue disorder in which excessive collagen is deposited in the skin and internal organs. 1404156 1992