Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.250 AlteredExpression disease BEFREE Our data suggest that some of the key profibrotic features of lesional SSc fibroblasts are dependent upon ALK-5 activity. 16575856 2006
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.250 AlteredExpression disease BEFREE Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma. 16947635 2006
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.250 AlteredExpression disease BEFREE The present study utilized previously a described model of scleroderma (SSc) fibrosis based on forced expression of the TGF-betaRI (ALK5) (Pannu, J., Gardner, H., Shearstone, J. R., Smith, E., and Trojanowska, M. (2006) Arthritis Rheum.54, 3011-3021). 17317656 2007
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.250 AlteredExpression disease BEFREE There was no significant difference in Smurf1 and Smurf2 levels between normal and scleroderma fibroblasts, and the transiently overexpressed Smurf1 and/or Smurf2 did not affect TGF-beta receptor type I protein levels in scleroderma fibroblasts. 14722617 2004
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.250 Biomarker disease BEFREE An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma. 15146427 2004
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.250 AlteredExpression disease LHGDN Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma. 16947635 2006
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.250 Biomarker disease MGD