| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.460 | Biomarker | phenotype | BEFREE | In addition, using a novel approach to quantifying glial activation, we show that expression of the astrocyte cytoskeletal marker glial fibrillary acidic protein (GFAP) following kainic acid (KA)-induced seizures or during ageing did not change in Tg hsIL-1ra animals. | 18279308 | 2008 | ||||
|
0.460 | AlteredExpression | phenotype | BEFREE | Treatment with WRPE attenuated epileptiform seizure scores to a half level in KA-challenged mice, and decreased hippocampal pyramidal neuronal injury and loss (cresyl violet and DAPI staining) as well as astrocyte activation (GFAP immunostaining). | 30261613 | 2018 | ||||
|
0.460 | Biomarker | phenotype | BEFREE | Serum concentrations of HMGB1, IL-1β, S-100B, and GFAP were significantly higher in the epilepsy group within 24 hours of a seizure episode than in the control group. | 30303442 | 2018 | ||||
|
0.460 | Biomarker | phenotype | GENOMICS_ENGLAND | Alexander disease: ventricular garlands and abnormalities of the medulla and spinal cord. | 16505300 | 2006 | ||||
|
0.460 | Biomarker | phenotype | HPO | |||||||
|
0.460 | Biomarker | phenotype | BEFREE | The role of UCH-L1, MMP-9, and GFAP as peripheral markers of different susceptibility to seizure development in a preclinical model of epilepsy. | 30952062 | 2019 | ||||
|
0.460 | GeneticVariation | phenotype | CLINVAR | |||||||
|
0.460 | AlteredExpression | phenotype | BEFREE | Glial fibrillary acidic protein (GFAP) expression showed no changes induced with LPS alone and rose slightly after seizures. | 28597918 | 2017 | ||||
|
0.460 | AlteredExpression | phenotype | BEFREE | In the present study, status epilepticus (SE, a prolonged seizure activity) led to reactive astrogliosis showing the increases in GFAP expression and the number of proliferating astrocytes with prolonged extracellular signal receptor-activated kinases 1/2 (ERK1/2) activation and reduced nuclear p27<sup>Kip1</sup> level. | 29930499 | 2018 |