| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | phenotype | BEFREE | Age, anaesthetic dose, ECT type and ECT treatment number also had a significant impact on measures of seizure quality (p < 0.05). | 30981950 | 2019 | ||||
|
0.070 | Biomarker | phenotype | BEFREE | Seizures were rated for overall seizure adequacy on a scale of 0-6, with one point given for each measure that was considered to be adequate according to the ECT literature: (1) seizure EEG duration (2) motor duration, (3) post-ictal suppression, (4) ictal EEG maximum amplitude, (5) Global Seizure Strength, and (6) Symmetry. | 29735419 | 2018 | ||||
|
0.070 | Biomarker | phenotype | BEFREE | Increases in seizure threshold (ST) over a course of brief pulse ECT can be predicted by decreases in EEG quality, informing ECT dose adjustment to maintain adequate supra-threshold dosing. | 28401340 | 2017 | ||||
|
0.070 | Biomarker | phenotype | BEFREE | Finally, the value of electric field and neural modelling is illustrated to explain observed clinical effects of modifications to ECT technique, and their utility in the rational design of the next generation of seizure therapies. | 28430533 | 2017 | ||||
|
0.070 | GeneticVariation | phenotype | BEFREE | To analyze the relationship between seizure threshold (ST) and psychotropic drugs in patients treated with ECT. | 29042890 | 2017 | ||||
|
0.070 | Biomarker | phenotype | BEFREE | We also tested pilocarpine-susceptible congenics for 6-Hz ECT (electroconvulsive threshold), another model of limbic seizure susceptibility, to determine whether the susceptibility locus might have a broad effect on neuronal hyperexcitability across more than one mode of limbic seizure induction. | 24373497 | 2014 | ||||
|
0.070 | Biomarker | phenotype | BEFREE | Phenotypic characterization of mice on different inbred strains includes behavioral monitoring and EEG analysis looking for the occurrence of spontaneous seizures, as well as routine cage examination looking for handling-provoked seizure and ECT- and PTZ- induced seizure paradigms looking for sensitivity to these stimuli. | 15250582 | 2004 |