| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | To address three controversial components in the Centers for Medicare and Medicaid Service's sepsis bundle for performance measure (SEP-1): antibiotics within 3 hours, a 30 mL/kg fluid infusion for all hypotensive patients, and repeat lactate measurements within 6 hours if initially elevated. | 31369426 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Sepsis quality in safety-net hospitals: An analysis of Medicare's SEP-1 performance measure. | 31400737 | 2019 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Implementation of an adult code sepsis protocol and its impact on SEP-1 core measure perfect score attainment in the ED. | 31301874 | 2019 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Randomized and observational studies of death among adults with sepsis who received versus those who did not receive either the entire SEP-1 bundle or 1 or more SEP-1 hemodynamic interventions, including serial lactate measurements; a fluid infusion of 30 mL/kg of body weight; and assessment of volume status and tissue perfusion with a focused examination, bedside cardiovascular ultrasonography, or fluid responsiveness testing. | 29459977 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Sepsis remains a significant cause of morbidity and mortality in the United States, leading to the implementation of the Severe Sepsis and Septic Shock Early Management Bundle (SEP-1). | 29804795 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | SEP-1 failures had higher rates of septic shock (20% vs 9%; p < 0.001), hospital-onset sepsis (11% vs 4%; p = 0.001), and vague presenting symptoms (46% vs 30%; p < 0.001). | 30015667 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Variability in determining sepsis time zero and bundle compliance rates for the centers for medicare and medicaid services SEP-1 measure. | 29932042 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Sepsis National Hospital Inpatient Quality Measure (SEP-1): Multistakeholder Work Group Recommendations for Appropriate Antibiotics for the Treatment of Sepsis. | 29048513 | 2017 |