| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | group | BEFREE | The microenvironment in cutaneous lesions of BD patients' skin lesions is dominated by the expression of IL-33 and TSLP along an inflammatory Th2-type current. | 29631029 | 2018 | ||||
|
0.080 | Biomarker | group | BEFREE | We also identified upregulated mRNA and protein expression of TLR1, TLR6, IL-25, and IL-33 in human atopic dermatitis skin lesions with high house dust mite sensitization. | 28684329 | 2017 | ||||
|
0.080 | AlteredExpression | group | BEFREE | The numbers of inflammatory cells expressing IL-33 and ST2 were elevated in skin lesions of patients with AOSD compared to HC, but did not differ from those of the skin lesions of eczema or psoriasis. | 28365573 | 2017 | ||||
|
0.080 | Biomarker | group | BEFREE | Hydrogen water administration also significantly reduced TEWL and serum TARC levels (p less than 0.01), infiltration of mast cells (p less than 0.05), and secretion of the proinflammatory cytokines interleukin (IL)-1β and IL-33 (p less than 0.05) in skin lesions compared with PW. | 28889151 | 2017 | ||||
|
0.080 | Biomarker | group | BEFREE | Levels of the epithelial cytokine IL-33 are increased in skin lesions and serum of patients with AD. | 27372570 | 2016 | ||||
|
0.080 | AlteredExpression | group | BEFREE | We found that IL-33/ST2L were positively expressed in the skin lesions of AD patients and a high expression of IL-33 was induced in keratinocytes by IL-4 plus interferon [IFN]-γ or IFN-γ alone at the mRNA and protein levels. | 27348082 | 2016 | ||||
|
0.080 | AlteredExpression | group | BEFREE | IL-33 mRNA expression in the skin lesions of patients with active BD was significantly increased compared to that in healthy skin biopsies [p=0.00016]. | 23464866 | 2013 | ||||
|
0.080 | Biomarker | group | BEFREE | Furthermore, injections of IL-33 into the ears of mice induce an inflammatory skin lesion. | 21674479 | 2011 |