| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | The heterozygous model showed a significant association between the miR-146a rs2910164 (G/C) polymorphism and ankylosing spondylitis (AS). | 31235484 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Mechanism studies further revealed that loss of DKK1 partly reversed the effect of miR-146a inhibitor on cell proliferation, apoptosis and osteogenic potential in AS fibroblasts. | 29145150 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | A low copy number of miR-146a and a high copy number of miR-23a and miR-205 were associated with AAU+AS-. | 28384720 | 2017 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In addition, expression level of miR-146a in PBMC of patients with AS was positively correlated with BASDAI, ESR, CRP and duration of morning stiffness (r=0.551, P<0.01; r=0.738, P<0.01; r=0.685, P<0.01; r=0.497, P<0.01). | 29201209 | 2017 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Selected miRNAs, such as miR-29a-3p, miR-146a-5p or miR-222-3p with an established role in extracellular matrix formation and inflammation were associated with spinal changes and/or disease activity assessed by BASDAI in AS patients, including miR-625-3p reflecting disease activity in AS with spinal involvement. | 28938006 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | Detection of serum miRNAs (miR-146a and miR-155) may serve as novel complementary biomarkers for AS. | 27128253 | 2016 | ||||
|
0.080 | Biomarker | disease | BEFREE | In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. | 26366721 | 2015 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The present study explored the association between ankylosing spondylitis (AS) and two single nucleotide polymorphisms (SNPs), miR-146a rs2910164G>C and miR-499 rs3746444T>C, in a Han Chinese population. | 25836258 | 2015 |