| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | Our meta-analysis demonstrated that the rs2227982 polymorphism in the PD-1 gene might contribute to AS susceptibility. | 26232179 | 2016 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The programmed cell death 1 gene polymorphisms (PD 1.3 G/A, PD 1.5 C/T and PD 1.9 C/T) and susceptibility to ankylosing spondylitis: a meta-analysis. | 25270018 | 2015 | ||||
|
0.090 | Biomarker | disease | BEFREE | HLA-B27 and PDCD-1 are potentially the useful markers of AS activity and useful parameters to evaluate the effectiveness of anti-TNF-α inhibitor in treating AS. | 25005770 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The purpose of this study is to investigate whether a single nucleotide polymorphism (SNP) in the exon region of the programmed cell death 1 (PDCD-1) gene is associated with the susceptibility or the thoracolumbar kyphosis severity of AS in a Chinese Han population. | 23620109 | 2013 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Effects of genetic polymorphisms of programmed cell death 1 and its ligands on the development of ankylosing spondylitis. | 21791547 | 2011 | ||||
|
0.090 | Biomarker | disease | BEFREE | There was no evidence of association for PDCD1 SNPs with AS in our study, but CT genotype (PD-1.9) seems to be associated with HLA-B27 positivity in the patients with AS. | 21161353 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The results support a major role for PD-1/PD-L1 polymorphisms in disease susceptibility of AS. | 21269571 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Moreover, the frequency of the CT haplotype (PD-1.5 C/T, PD-1.9 T/C) was significantly higher in AS patients than the controls (21.6 vs. 13.9%, P = 0.002). | 20012629 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Association of the programmed cell death 1 (PDCD1) gene polymorphism with ankylosing spondylitis in the Korean population. | 17064404 | 2006 |