Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.700 GeneticVariation group BEFREE Also, eIF2α-P stimulation by the phosphatase inhibitor SAL003 substantially increases Trastuzumab potency in resistant HER2+ breast and gastric tumors. 31086176 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.700 GeneticVariation group LHGDN A single nucleotide polymorphism in the transmembrane domain coding region of HER-2 is associated with development and malignant phenotype of gastric cancer. 14520697 2003
Entrez Id: 324
Gene Symbol: APC
APC 		0.640 GeneticVariation group BEFREE These results suggest that genetic alteration of a region of APC commonly mutated in colorectal cancer is not a common event during sporadic gastric tumor development, at least in patients from North-Central Italy. 8649856 1996
Entrez Id: 324
Gene Symbol: APC
APC 		0.640 GeneticVariation group CLINVAR
Entrez Id: 324
Gene Symbol: APC
APC 		0.640 GeneticVariation group BEFREE Mutations in the human APC gene are linked to familial adenomatous polyposis and to the progression of sporadic colorectal and gastric tumors. 8259518 1993
Entrez Id: 324
Gene Symbol: APC
APC 		0.640 GeneticVariation group BEFREE Endoscopic findings of GN and background mucosa, and histopathological findings, including phenotypic expression of GN and mutation locus of adenomatous polyposis coli (APC) gene, were evaluated. 31411765 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.620 GeneticVariation group BEFREE Only when the tumors were located in the middle-third of stomach, tumor with mutations of the PIK3CA gene or mutations of the PI3K/AKT pathway genes were associated with more EBV infection than those without mutations. 26701847 2016
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		0.620 GeneticVariation group CLINVAR
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 GeneticVariation group LHGDN Genetic alterations of the MYH gene in gastric cancer. 15273732 2004
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		0.610 GeneticVariation group LHGDN Genetic alterations of the KLF6 gene in gastric cancer. 15824733 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 GeneticVariation group CLINVAR
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. 17545690 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. 15235021 2004
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain. 16870389 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Association between CDH1 haplotypes and gastric cancer risk in a Japanese population. 17852867 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Single nucleotide polymorphisms in the promoter region of the E-cadherin gene in gastric cancer: case-control study in a young Mexican population. 17549573 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population. 18482459 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN E-cadherin and hereditary diffuse gastric cancer. 17981184 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Germline E-cadherin mutations in familial lobular breast cancer. 17660459 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family. 17126523 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer. 12444556 2002
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Hereditary diffuse gastric cancer: association with lobular breast cancer. 18046629 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN CDH1/E-cadherin germline mutations in early-onset gastric cancer. 16801346 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management. 16061854 2005
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.600 GeneticVariation group LHGDN E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer. 12216071 2002