×
Entrez Id: 324
Gene Symbol: APC
APC
0.640
GeneticVariation
group
BEFREE
These results suggest that genetic alteration of a region of APC commonly mutated in colorectal cancer is not a common event during sporadic gastric tumor development, at least in patients from North-Central Italy.
8649856 1996
×
Entrez Id: 324
Gene Symbol: APC
APC
0.640
GeneticVariation
group
BEFREE
Mutations in the human APC gene are linked to familial adenomatous polyposis and to the progression of sporadic colorectal and gastric tumors .
8259518 1993
×
Entrez Id: 324
Gene Symbol: APC
APC
0.640
Biomarker
group
HPO
×
Entrez Id: 324
Gene Symbol: APC
APC
0.640
Biomarker
group
CTD_human
×
Entrez Id: 324
Gene Symbol: APC
APC
0.640
CausalMutation
group
CLINVAR
×
Entrez Id: 324
Gene Symbol: APC
APC
0.640
GeneticVariation
group
CLINVAR
×
Entrez Id: 324
Gene Symbol: APC
APC
0.640
CausalMutation
group
CGI
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.620
GeneticVariation
group
BEFREE
Only when the tumors were located in the middle-third of stomach, tumor with mutations of the PIK3CA gene or mutations of the PI3K/AKT pathway genes were associated with more EBV infection than those without mutations.
26701847 2016
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.620
Biomarker
group
CTD_human
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.
22484628 2012
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.620
Biomarker
group
CTD_human
Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy.
21173787 2012
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.620
Biomarker
group
CTD_human
Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.
21936542 2011
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.620
AlteredExpression
group
LHGDN
FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.
18381441 2008
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.620
PosttranslationalModification
group
LHGDN
Aberrant hypermethylation of the FGFR2 gene in human gastric cancer cell lines.
17459342 2007
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.620
AlteredExpression
group
LHGDN
Mutations of PIK3CA in gastric adenocarcinoma.
15784156 2005
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.620
CausalMutation
group
CLINVAR
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.620
Biomarker
group
HPO
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.620
GeneticVariation
group
CLINVAR
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.620
GenomicAlterations
group
CGI
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.620
CausalMutation
group
CLINVAR
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.620
CausalMutation
group
CGI
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.620
CausalMutation
group
CGI
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.
24728327 2014
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
MUTYH-associated polyposis (MAP): evidence for the origin of the common European mutations p.Tyr179Cys and p.Gly396Asp by founder events.
23361220 2014
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Personalized genomic disease risk of volunteers.
24082139 2013
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability.
23108399 2013