×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells.
22926731
2012
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.
11818965
2002
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis.
20418187
2010
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
Biomarker
group
CTD_human
×
Entrez Id:
1316
Gene Symbol:
KLF6
KLF6
0.610
CausalMutation
group
CLINVAR
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Personalized genomic disease risk of volunteers.
24082139
2013
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis.
19032956
2009
×
Entrez Id:
1316
Gene Symbol:
KLF6
KLF6
0.610
Biomarker
group
CTD_human
×
Entrez Id:
1316
Gene Symbol:
KLF6
KLF6
0.610
GeneticVariation
group
LHGDN
Genetic alterations of the KLF6 gene in gastric cancer.
15824733
2005
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants.
21063410
2010
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay.
19953527
2010
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
High prevalence of the c.1227_1228dup (p.Glu410GlyfsX43) mutation in Tunisian families affected with MUTYH-associated-polyposis.
22744763
2012
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
MUTYH gene expression and alternative splicing in controls and polyposis patients.
22473953
2012
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
MutYH mutation carriers have increased breast cancer risk.
21952991
2012
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability.
23108399
2013
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer.
19836313
2009
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
GeneticVariation
group
CLINVAR
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis.
21178863
2010
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.
24728327
2014
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Biallelic MYH germline mutations as cause of Muir-Torre syndrome.
19998059
2010
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome.
23805267
2013
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
MUTYH-associated polyposis (MAP): evidence for the origin of the common European mutations p.Tyr179Cys and p.Gly396Asp by founder events.
23361220
2014
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes.
22703879
2012
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Expanded extracolonic tumor spectrum in MUTYH-associated polyposis.
19732775
2009
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
CausalMutation
group
CLINVAR
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
20848659
2010