×
Entrez Id:
1316
Gene Symbol:
KLF6
KLF6
0.610
Biomarker
group
CTD_human
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
GeneticVariation
group
CLINVAR
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
BEFREE
This multicenter study evaluated the association of 9 single nucleotide polymorphisms (SNP) in AXIN2 and CDH1 , representing genes consistently altered in breast and gastric tumors , with NSCL ± P in 223 trios (father, mother and patient with NSCL ± P) by transmission disequilibrium test (TDT).
28376813
2017
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
CTD_human
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
24816253
2014
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
BEFREE
Despite advances with traditional single genes molecular research, including rare mutations in BRCA1/2 and CDH1 for primary prevention and trastuzumab for treating HER2-overexpressing breast and gastric tumors , overall, treatment failure and death rates are still alarmingly high.
20975737
2011
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
CTD_human
Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa.
19184424
2010
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
CTD_human
Germline CDH1 deletions in hereditary diffuse gastric cancer families.
19168852
2009
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
AlteredExpression
group
LHGDN
The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers.
18427545
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
LHGDN
Positive association of up-regulated Cripto-1 and down-regulated E-cadherin with tumour progression and poor prognosis in gastric cancer.
18312357
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population.
18482459
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Hereditary diffuse gastric cancer: association with lobular breast cancer.
18046629
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
AlteredExpression
group
LHGDN
Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells.
18377425
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.
17545690
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Association between CDH1 haplotypes and gastric cancer risk in a Japanese population.
17852867
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Single nucleotide polymorphisms in the promoter region of the E-cadherin gene in gastric cancer: case-control study in a young Mexican population.
17549573
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
LHGDN
Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells.
17396032
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
E-cadherin and hereditary diffuse gastric cancer.
17981184
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Germline E-cadherin mutations in familial lobular breast cancer.
17660459
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family.
17126523
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene.
17221870
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain.
16870389
2006
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
CDH1/E-cadherin germline mutations in early-onset gastric cancer.
16801346
2006
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
LHGDN
Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin.
16132582
2005
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management.
16061854
2005
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
CDH1 associated gastric cancer: a report of a family and review of the literature.
15780560
2005