Gene: MUTYH ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing. 24728327 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR MUTYH-associated polyposis (MAP): evidence for the origin of the common European mutations p.Tyr179Cys and p.Gly396Asp by founder events. 23361220 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Personalized genomic disease risk of volunteers. 24082139 2013
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability. 23108399 2013
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome. 23805267 2013
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Colorectal cancer in a monoallelic MYH mutation carrier. 23625202 2013
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells. 22926731 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR High prevalence of the c.1227_1228dup (p.Glu410GlyfsX43) mutation in Tunisian families affected with MUTYH-associated-polyposis. 22744763 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR MUTYH gene expression and alternative splicing in controls and polyposis patients. 22473953 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR MutYH mutation carriers have increased breast cancer risk. 21952991 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes. 22703879 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR MUTYH-associated colon disease: adenomatous polyposis is only one of the possible phenotypes. A family report and literature review. 22158503 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis. 20418187 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants. 21063410 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay. 19953527 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis. 21178863 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Biallelic MYH germline mutations as cause of Muir-Torre syndrome. 19998059 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. 20848659 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis. 19032956 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer. 19836313 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Expanded extracolonic tumor spectrum in MUTYH-associated polyposis. 19732775 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Characterization of mutant MUTYH proteins associated with familial colorectal cancer. 18534194 2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 GeneticVariation group LHGDN Genetic alterations of the MYH gene in gastric cancer. 15273732 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CLINVAR Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors. 11818965 2002
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.610 CausalMutation group CGI