Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group CTD_human A genetic variant in 3'-untranslated region of cyclooxygenases-2 gene is associated with risk of gastric cancer in a Chinese population. 22385256 2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group LHGDN Positive correlation of osteopontin, cyclooxygenase-2 and vascular endothelial growth factor in gastric cancer. 18181047 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Cyclooxygenase-2 expression and its association with angiogenesis, Helicobacter pylori, and clinicopathologic characteristics of gastric carcinoma. 18462890 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 18373164 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Bile acid induces expression of COX-2 through the homeodomain transcription factor CDX1 and orphan nuclear receptor SHP in human gastric cancer cells. 18775915 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 GeneticVariation group LHGDN The COX-2 promoter polymorphism -765 G>C is associated with early-onset, conventional and stump gastric cancers. 18311113 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group CTD_human Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 17003101 2007
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Targeted inhibition of COX-2 expression by RNA interference suppresses tumor growth and potentiates chemosensitivity to cisplatin in human gastric cancer cells. 17982644 2007
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group CTD_human Effect of celecoxib on E-cadherin, VEGF, Microvessel density and apoptosis in gastric cancer. 17224647 2007
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Celecoxib could reverse the hypoxia-induced Angiopoietin-2 upregulation in gastric cancer. 16338068 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group LHGDN Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers. 16474375 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Proapoptotic activity of NAG-1 is cell type specific and not related to COX-2 expression. 16699947 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells. 16371352 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Increased expression of interleukin-1alpha and cyclooxygenase-2 in human gastric cancer: a possible role in tumor progression. 16101131 2005
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group LHGDN Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR. 16243808 2005
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Expression of cyclooxygenase-2 in gastric cancer and its relation to liver metastasis and long-term prognosis. 16097070 2005
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 PosttranslationalModification group LHGDN Mechanism and clinical significance of cyclooxygenase-2 expression in gastric cancer. 15929174 2005
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group BEFREE We further studied the action of COX-2 on other proto-oncogenes on gastric tumor growth. 14962510 2004
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Expression of COX-2 proteins in gastric mucosal lesions. 14716842 2004
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 PosttranslationalModification group LHGDN Promoter hypermethylation of cyclooxygenase-2 in gastric carcinoma. 12684668 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group LHGDN Increased abundance of cyclooxygenase-2 correlates with vascular endothelial growth factor-A abundance and tumor angiogenesis in gastric cancer. 12767510 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN Association of cyclooxygenase-2 expression with Hp-cagA infection in gastric cancer. 12532440 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 AlteredExpression group LHGDN [Significance of COX-2, p53, proliferating cell nuclear antigen and nm23 expressions in gastric cancer and its behavior]. 12452062 2002
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group CTD_human Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability. 10404093 1999