Gene: TP53 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group BEFREE Among germline TP53 mutation carriers, increased residual transcriptional activity is correlated with prolonged lifetime cancer survival and delayed tumor onset, and males are more prone to develop brain and gastric tumors. 30089713 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 AlteredExpression group BEFREE Increased levels of TRIM59 in human gastric tumors correlated with reduced expression of P53 target genes. 25046164 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group BEFREE Deletion of one copy of FBXW7 and TP53 was observed in 45.5% and 21.2% of gastric tumors, respectively. 24053468 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group CTD_human Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 22484628 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group BEFREE Nevertheless, C carriers with a high D17S250 microsatellite instability (TP53 gene) show a higher risk to develop gastric tumors (P = 0.0453; OR: 4.1556-IC95%: 0.9716-17.7728), suggesting that the mutate TP53 gene may fail in control and inhibition of Survivin expression, favoring the gastric carcinogenesis. 21161671 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group BEFREE In humans, we found SRF and Enigma coexpressed with MDM2 but not p53 in several liver and stomach tumors. 21060154 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 AlteredExpression group LHGDN Maspin and p53 protein expression in gastric adenocarcinoma and its clinical applications. 18091326 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group LHGDN p53 is an indicator of tumor progression in early but not advanced gastric carcinomas. 18251181 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group LHGDN Clinicopathologic significance of HIF-1alpha, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer. 18452596 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group LHGDN Prognostic role of p53 codon 72 polymorphism in gastric cancer patients treated with fluorouracil-based adjuvant chemotherapy. 18357466 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group LHGDN Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. 18803879 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group LHGDN Class I phosphatidylinositol 3-kinase inhibitor LY294002 activates autophagy and induces apoptosis through p53 pathway in gastric cancer cell line SGC7901. 18330473 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group LHGDN A solitary colonic metastasis from gastric cancer detected at an early stage. 18291388 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group LHGDN P53 codon 72 polymorphism and gastric cancer: a meta-analysis of the literature. 17546594 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group BEFREE The data on p53 abnormalities, when considered separately, could be of relative value for predicting the behavior of gastric tumors. 17436385 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group LHGDN Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. 17638920 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 AlteredExpression group LHGDN The data on p53 abnormalities, when considered separately, could be of relative value for predicting the behavior of gastric tumors. 17436385 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 AlteredExpression group LHGDN Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population. 17690113 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group LHGDN A p53 genetic polymorphism of gastric cancer: difference between early gastric cancer and advanced gastric cancer. 17072987 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group LHGDN Overexpression of hypoxia-inducible factor 1alpha and p53 is a marker for an unfavorable prognosis in gastric cancer. 16951228 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group LHGDN P53 genetic polymorphism of gastric cancer in Korea. 16646561 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 AlteredExpression group LHGDN The evaluation of gastric cancer sensitivity to 5-FU/CDDP in terms of induction of apoptosis: time- and p53 expression-dependency of anti-cancer drugs. 16077963 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group LHGDN Role of p53 codon 72 polymorphism in the risk of development of distal gastric cancer. 15841715 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 GeneticVariation group LHGDN P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population. 15069555 2004