Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group BEFREE This multicenter study evaluated the association of 9 single nucleotide polymorphisms (SNP) in AXIN2 and CDH1, representing genes consistently altered in breast and gastric tumors, with NSCL ± P in 223 trios (father, mother and patient with NSCL ± P) by transmission disequilibrium test (TDT). 28376813 2017
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 Biomarker group CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 Biomarker group BEFREE Despite advances with traditional single genes molecular research, including rare mutations in BRCA1/2 and CDH1 for primary prevention and trastuzumab for treating HER2-overexpressing breast and gastric tumors, overall, treatment failure and death rates are still alarmingly high. 20975737 2011
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 Biomarker group CTD_human Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa. 19184424 2010
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 Biomarker group CTD_human Germline CDH1 deletions in hereditary diffuse gastric cancer families. 19168852 2009
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 AlteredExpression group LHGDN The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. 18427545 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 Biomarker group LHGDN Positive association of up-regulated Cripto-1 and down-regulated E-cadherin with tumour progression and poor prognosis in gastric cancer. 18312357 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population. 18482459 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Hereditary diffuse gastric cancer: association with lobular breast cancer. 18046629 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 AlteredExpression group LHGDN Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. 18377425 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. 17545690 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Association between CDH1 haplotypes and gastric cancer risk in a Japanese population. 17852867 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Single nucleotide polymorphisms in the promoter region of the E-cadherin gene in gastric cancer: case-control study in a young Mexican population. 17549573 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 Biomarker group LHGDN Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells. 17396032 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN E-cadherin and hereditary diffuse gastric cancer. 17981184 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Germline E-cadherin mutations in familial lobular breast cancer. 17660459 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family. 17126523 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene. 17221870 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain. 16870389 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN CDH1/E-cadherin germline mutations in early-onset gastric cancer. 16801346 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 Biomarker group LHGDN Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin. 16132582 2005
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management. 16061854 2005
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN CDH1 associated gastric cancer: a report of a family and review of the literature. 15780560 2005
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 Biomarker group LHGDN Clinical significance of dysadherin expression in gastric cancer patients. 15102690 2004
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.600 GeneticVariation group LHGDN Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. 15235021 2004