Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
0.020 Biomarker disease BEFREE In contrast, The ABC pattern of EPIYA motif was less frequent in the H. pylori isolates from GU (41/50, 82%) than in those from CG (80/81, 98.80%) (Age-sex-adjusted odds ratio (OR) = 0.020, 95% CI = 0.002-0.259; P = 0.003). 26408373 2015
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
0.020 Biomarker disease BEFREE The types of EPIYA motif detected by PCR among 28 DU strains were 13 ABC, eight ABCC, six ABCCC, and in one patient both ABC and ABCCCCC; among nine GU strains were two ABC, five ABCC and two ABCCC; and among 40 gastritis strains were 35 ABC and five ABCC. 19850704 2010
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.010 GeneticVariation disease BEFREE We assessed CMA/B A/G and ACE insertion/deletion (I/D) polymorphisms in H. pylori-positive gastric cancers (n = 119), gastric ulcers (n = 127), and duodenal ulcers (n = 105), and controls (n = 294) consisting of H. pylori-positive gastritis alone (n = 162) and H. pylori-negative subjects (n = 132) by PCR methods. 17035401 2006
Entrez Id: 60
Gene Symbol: ACTB
ACTB
0.010 Biomarker disease BEFREE The relative mean level of TERT mRNA after normalization with the β-actin reference gene and comparison with the respective adjacent normal mucosa was slightly increased in the IM and GU groups, 2.008 ± 2.605 and 2.730 ± 4.120, respectively, but high TERT mRNA expression was observed in the GC group (17.271 ± 33.852). 21180888 2011
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.010 AlteredExpression disease BEFREE Higher expression levels of ADAM17 and Th17 cytokines (IL-17A and IL-23), and their strong correlation with GU and intestinal-type GC patients in the presence of H. pylori and its intact cagPAI status, suggest a possible role of strain specificity in the pathogenesis of these diseases. 30371773 2018
Entrez Id: 133
Gene Symbol: ADM
ADM
0.300 Therapeutic disease CTD_human Effects of centrally of peripherally injected adrenomedullin on reserpine-induced gastric lesions. 9845272 1998
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
0.010 Biomarker disease BEFREE Beta(3)-adrenoceptor agonists protect against experimental gastric ulcers. 18492028 2008
Entrez Id: 183
Gene Symbol: AGT
AGT
0.210 GeneticVariation disease BEFREE We assessed the AGT-20 A/C polymorphism in Helicobacter pylori-positive patients with gastric cancer (n = 135), gastric ulcer (n = 148) and duodenal ulcer (n = 113) and controls (n = 292) consisting of H.pylori-positive gastritis alone (n = 160) and H.pylori-negative subjects (n = 132). 17389608 2007
Entrez Id: 183
Gene Symbol: AGT
AGT
0.210 Therapeutic disease RGD Angiotensin (1-7) protects against stress-induced gastric lesions in rats. 24231511 2014
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
0.210 AlteredExpression disease BEFREE These studies demonstrated that a single local injection of plasmids expressing vascular endothelial growth factor and angiopoietin-1 dramatically accelerates the healing of duodenal, gastric and esophageal gastric ulcers. 16628261 2006
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
0.210 Biomarker disease RGD The purpose of this study was to evaluate the expression of Tie-2 and Ang-1 and -2 in an acetic acid-induced gastric ulcer healing process in rats. 12768384 2003
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
0.200 Biomarker disease RGD Expression of Tie-2 and angiopoietin-1 and -2 in early phase of ulcer healing. 12768384 2003
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
0.010 Biomarker disease BEFREE Immunohistochemistry revealed significant positive staining for both the AnxA1 and Gal-1 proteins in the epithelial nucleus and cytoplasm as well as in the stroma of the IM and GU groups (P < 0.05) but absence or low immunorectivity in normal mucosa. 24719523 2014
Entrez Id: 57492
Gene Symbol: ARID1B
ARID1B
0.100 Biomarker disease HPO
Entrez Id: 572
Gene Symbol: BAD
BAD
0.200 Therapeutic disease RGD Cytoprotective effect of American ginseng in a rat ethanol gastric ulcer model. 24378970 2013
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.200 Therapeutic disease RGD Cytoprotective effect of American ginseng in a rat ethanol gastric ulcer model. 24378970 2013
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
0.200 Therapeutic disease RGD Cytoprotective effect of American ginseng in a rat ethanol gastric ulcer model. 24378970 2013
Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1
0.010 AlteredExpression disease LHGDN Comparison of tissue kallikrein and kinin receptor expression in gastric ulcers and neoplasms. 11710536 2001
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
0.010 AlteredExpression disease LHGDN Comparison of tissue kallikrein and kinin receptor expression in gastric ulcers and neoplasms. 11710536 2001
Entrez Id: 100128998
Gene Symbol: C20orf181
C20orf181
0.010 Biomarker disease BEFREE This study was designed to investigate associations of t-PA and PAI-1 genes with clinical features of the patients with bleeding gastric ulcers. 12589088 2003
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.200 Therapeutic disease RGD Prophylactic efficacy of patchoulene epoxide against ethanol-induced gastric ulcer in rats: Influence on oxidative stress, inflammation and apoptosis. 29339218 2018
Entrez Id: 847
Gene Symbol: CAT
CAT
0.500 Therapeutic disease CTD_human Role of oxygen-derived free radicals in indomethacin-induced gastric injury. 1887894 1991
Entrez Id: 847
Gene Symbol: CAT
CAT
0.500 Biomarker disease RGD Gastroprotective and antioxidant effects of montelukast on indomethacin-induced gastric ulcer in rats. 17895592 2007
Entrez Id: 885
Gene Symbol: CCK
CCK
0.300 Biomarker disease CTD_human Involvement of capsaicin-sensitive afferent nerves and cholecystokinin 2/gastrin receptors in gastroprotection and adaptation of gastric mucosa to Helicobacter pylori-lipopolysaccharide. 15024038 2004
Entrez Id: 885
Gene Symbol: CCK
CCK
0.300 Biomarker disease CTD_human Central leptin and cholecystokinin in gastroprotection against ethanol-induced damage. 11025360 2000