Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_mouse Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice. 21078376 2011
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Biomarker disease CTD_human Antidiabetic effect of SN158 through PPARα/γ dual activation in ob/ob mice. 28242381 2017
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker disease CTD_human Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor Cells. 27151219 2016
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker disease CTD_human Octaphlorethol A, a marine algae product, exhibits antidiabetic effects in type 2 diabetic mice by activating AMP-activated protein kinase and upregulating the expression of glucose transporter 4. 26939912 2016
Entrez Id: 8660
Gene Symbol: IRS2
IRS2 		0.300 Biomarker disease CTD_human Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1-independent manner. 25808216 2015
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker disease CTD_human Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy. 24263156 2014
Entrez Id: 412
Gene Symbol: STS
STS 		0.300 Therapeutic disease CTD_human Hepatic overexpression of steroid sulfatase ameliorates mouse models of obesity and type 2 diabetes through sex-specific mechanisms. 24497646 2014
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.300 Therapeutic disease CTD_human Reducing blood glucose levels in TIDM mice with an orally administered extract of sericin from hIGF-I-transgenic silkworm cocoons. 24632065 2014
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		0.300 Therapeutic disease CTD_human Increased vulnerability to β-cell destruction and diabetes in mice lacking NAD(P)H:quinone oxidoreductase 1. 23458895 2013
Entrez Id: 581
Gene Symbol: BAX
BAX 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Protective effects of chronic resveratrol treatment on vascular inflammatory injury in streptozotocin-induced type 2 diabetic rats: Role of NF-kappa B signaling. 24513509 2013
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 26291
Gene Symbol: FGF21
FGF21 		0.300 Therapeutic disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.300 Biomarker disease CTD_human Protective effects of chronic resveratrol treatment on vascular inflammatory injury in streptozotocin-induced type 2 diabetic rats: Role of NF-kappa B signaling. 24513509 2013
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3 		0.300 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013
Entrez Id: 2101
Gene Symbol: ESRRA
ESRRA 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1 		0.300 Biomarker disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.300 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013