Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5730
Gene Symbol: PTGDS
PTGDS
0.040 GeneticVariation disease BEFREE <b>Abbreviations</b>: CD, Cook's distance; DSM, Diagnostic and Statistical Manual of Mental Disorders; (G)RR, general (and specific) resistance resources; IES(-R), Impact of Event Scale (Revised); PDS, Posttraumatic Stress Diagnostic Scale; PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses; PTSD, post-traumatic stress disorder; SDR, standard deleted residual; SOC, sense of coherence; SOC-R, Sense of Coherence Scale - Revised. 30693079 2019
Entrez Id: 5172
Gene Symbol: SLC26A4
SLC26A4
0.040 GeneticVariation disease BEFREE <b>Abbreviations</b>: CD, Cook's distance; DSM, Diagnostic and Statistical Manual of Mental Disorders; (G)RR, general (and specific) resistance resources; IES(-R), Impact of Event Scale (Revised); PDS, Posttraumatic Stress Diagnostic Scale; PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses; PTSD, post-traumatic stress disorder; SDR, standard deleted residual; SOC, sense of coherence; SOC-R, Sense of Coherence Scale - Revised. 30693079 2019
Entrez Id: 8436
Gene Symbol: CAVIN2
CAVIN2
0.010 GeneticVariation disease BEFREE <b>Abbreviations</b>: CD, Cook's distance; DSM, Diagnostic and Statistical Manual of Mental Disorders; (G)RR, general (and specific) resistance resources; IES(-R), Impact of Event Scale (Revised); PDS, Posttraumatic Stress Diagnostic Scale; PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses; PTSD, post-traumatic stress disorder; SDR, standard deleted residual; SOC, sense of coherence; SOC-R, Sense of Coherence Scale - Revised. 30693079 2019
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.100 Biomarker disease BEFREE <b>Conclusion</b>: i-CBT appears a potentially acceptable intervention for adults with PTSD. 31497259 2019
Entrez Id: 1629
Gene Symbol: DBT
DBT
0.020 Biomarker disease BEFREE <b>Conclusion</b>: The outcome suggests that outpatient DBT-PTSD can safely be used to reduce PTSD symptoms and comorbid psychopathology in adults who have experienced CSA. 29372016 2018
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
0.010 Biomarker disease BEFREE <b>Conclusion.</b> It is possible that the lower level of transcriptional factors: HSF-1, NF-kB and Hif-1 as well as IL6 m-RNA may be associated with the effect of the PTSD patient's treatment. 28664719 2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.010 Biomarker disease BEFREE <b>Conclusion.</b> It is possible that the lower level of transcriptional factors: HSF-1, NF-kB and Hif-1 as well as IL6 m-RNA may be associated with the effect of the PTSD patient's treatment. 28664719 2017
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
0.010 Biomarker disease BEFREE <b>Conclusion.</b> It is possible that the lower level of transcriptional factors: HSF-1, NF-kB and Hif-1 as well as IL6 m-RNA may be associated with the effect of the PTSD patient's treatment. 28664719 2017
Entrez Id: 57142
Gene Symbol: RTN4
RTN4
0.010 Biomarker disease BEFREE <b>Conclusions.</b> ERPs in a GO/NOGO task can be used in the assessment of the functional brain changes induced by chronic PTSD. 28664706 2017
Entrez Id: 9033
Gene Symbol: PKD2L1
PKD2L1
0.100 GeneticVariation disease BEFREE <b>Method</b>: Three groups of asylum seekers from different countries (<i>N</i> = 99) completed the Traumatic Grief Inventory Self-Report Version (TGI-SR), Posttraumatic Stress Disorder Checklist-5 (PCL-5), and Patient Health Questionnaire depression module (PHQ-9). 30988893 2019
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
0.100 GeneticVariation disease BEFREE <b>Method</b>: Three groups of asylum seekers from different countries (<i>N</i> = 99) completed the Traumatic Grief Inventory Self-Report Version (TGI-SR), Posttraumatic Stress Disorder Checklist-5 (PCL-5), and Patient Health Questionnaire depression module (PHQ-9). 30988893 2019
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
0.100 GeneticVariation disease BEFREE <b>Methods</b>: Thirty-three patients newly admitted to an inpatient unit for treatment of trauma-related disorders received a standardized self-assessment package, including the PTSD Checklist for DSM-5 (PCL-5), the Moral Injury Events Scale (MIES; adapted for the Canadian context), and the Adverse Childhood Experiences Questionnaire (ACE-Q), which is a retrospective measure of childhood abuse. 30693070 2019
Entrez Id: 9033
Gene Symbol: PKD2L1
PKD2L1
0.100 GeneticVariation disease BEFREE <b>Methods</b>: Thirty-three patients newly admitted to an inpatient unit for treatment of trauma-related disorders received a standardized self-assessment package, including the PTSD Checklist for DSM-5 (PCL-5), the Moral Injury Events Scale (MIES; adapted for the Canadian context), and the Adverse Childhood Experiences Questionnaire (ACE-Q), which is a retrospective measure of childhood abuse. 30693070 2019
Entrez Id: 9033
Gene Symbol: PKD2L1
PKD2L1
0.100 Biomarker disease BEFREE <b>Methods:</b> The sample was composed of 205 Portuguese women who had been given a breast cancer diagnosis (<i>M</i> = 54.32, <i>SD</i> = 10.05), and who completed the following self-administered questionnaires: the Posttraumatic Stress Disorder Checklist (PCL-C); the Posttraumatic Growth Inventory (PTGI); the Core Beliefs Inventory; and the Event Related Rumination Inventory. 30618899 2018
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
0.100 Biomarker disease BEFREE <b>Methods:</b> The sample was composed of 205 Portuguese women who had been given a breast cancer diagnosis (<i>M</i> = 54.32, <i>SD</i> = 10.05), and who completed the following self-administered questionnaires: the Posttraumatic Stress Disorder Checklist (PCL-C); the Posttraumatic Growth Inventory (PTGI); the Core Beliefs Inventory; and the Event Related Rumination Inventory. 30618899 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker disease BEFREE <b>Methods:</b> We conducted a search for articles in PubMed, Scopus, PsycINFO, and Web of Science, using the key words: ("Child sexual abuse" OR "childhood maltreatment" OR "sexual violence" OR "posttraumatic stress disorder" OR "rape") AND ("cytokines" OR "inflammatory markers" OR "interleukin" OR "tumor necrosis factor" OR "C-reactive protein"). 30127754 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE <b>Methods:</b> We conducted a search for articles in PubMed, Scopus, PsycINFO, and Web of Science, using the key words: ("Child sexual abuse" OR "childhood maltreatment" OR "sexual violence" OR "posttraumatic stress disorder" OR "rape") AND ("cytokines" OR "inflammatory markers" OR "interleukin" OR "tumor necrosis factor" OR "C-reactive protein"). 30127754 2018
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
0.100 Biomarker disease BEFREE <b>Objective</b>: This study aimed to determine optimally efficient cut-off values for the Impact of Event Scale-Revised (IES-R) and the PTSD Checklist for DSM-5 (PCL-5) that can be used to assess for differential diagnosis of presumptive PTSD. 29435200 2017
Entrez Id: 9033
Gene Symbol: PKD2L1
PKD2L1
0.100 Biomarker disease BEFREE <b>Objective</b>: This study aimed to determine optimally efficient cut-off values for the Impact of Event Scale-Revised (IES-R) and the PTSD Checklist for DSM-5 (PCL-5) that can be used to assess for differential diagnosis of presumptive PTSD. 29435200 2017
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.060 GeneticVariation disease BEFREE <b>Objective</b>: This study examined the construct validity of two widely-used instruments for the assessment of PTSD symptoms (Harvard Trauma Questionnaire [HTQ]; 16 items) and symptoms of anxiety and depression (Hopkins Symptom Check list-25 [HSCL-25]; 25 items) among Dutch and refugee patients with different linguistic backgrounds. 29038686 2017
Entrez Id: 828
Gene Symbol: CAPS
CAPS
0.100 Biomarker disease BEFREE <b>Results</b>: Large effect sizes were achieved for PTSD symptom reduction on CAPS and the PSS-SR, both for patients with DS and those without. 29805779 2018
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.100 GeneticVariation disease BEFREE <b>Results:</b> Statistical genetics analysis identified a <i>DRD2/ANNK1</i>-<i>COMT</i> interaction (rs1800497 × rs6269), which is associated with PTSD diagnosis (<i>P</i><sub>interaction</sub> = 0.0008055 and <i>P</i><sub>corrected</sub> = 0.0169155). 29760667 2018
Entrez Id: 1621
Gene Symbol: DBH
DBH
0.020 AlteredExpression disease BEFREE (2007) reported a PTSD-associated deficit in serum DβH activity in a genotype-controlled analysis of combat veterans. 20621148 2010
Entrez Id: 117
Gene Symbol: ADCYAP1R1
ADCYAP1R1
0.100 GeneticVariation disease BEFREE (2011); Nature 470:492-497] demonstrated that a variant, rs2267735, in the gene encoding PAC1 (ADCYAP1R1) is associated with post-traumatic stress disorder (PTSD) in a primarily African-American cohort of highly traumatized females. 23505260 2013
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1
0.020 Biomarker disease BEFREE 152 female inbred DBA/2 J mice were submitted to an inescapable footshock paradigm to induce a PTSD-like condition (PTSDLC) and to a paradigm of locomotor sensitization to ethanol. 30986492 2019