Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.060 Biomarker disease BEFREE Resolution of synovitis and arrest of catabolic and anabolic bone changes in patients with psoriatic arthritis by IL-17A blockade with secukinumab: results from the prospective PSARTROS study. 30053825 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.060 Biomarker disease BEFREE Collectively, our data suggest that activation of a CD31-driven, αβTCR-independent, IL-17A-mediated T cell-FLC inflammatory circuit drives and/or perpetuates synovitis. 30127787 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.060 Biomarker disease BEFREE Similar observations apply for rheumatoid arthritis (RA) where IL-17A triggers changes in the synovium that lead to synovitis and maintain local inflammation. 30693283 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.060 Biomarker disease BEFREE Injured synovia exhibited increased synovitis grade and higher degree of IL-17A and SDF-1α immunostaining. 28284998 2017
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.060 Biomarker disease BEFREE However, mast cells expressed significantly more interleukin-17 (IL-17) in SpA than in RA synovitis, and mast cells constituted the major IL-17-expressing cell population in the SpA synovium. 21968742 2012
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.060 AlteredExpression disease BEFREE Pannus and synovitis fibroblasts explanted from tissue samples were cultured in vitro without and with TNF-alpha, IL-1Beta or IL-17 and analyzed quantitatively for RANKL expression. 18565244 2008