Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 GeneticVariation phenotype BEFREE In the last 5 years, nine new genes whose mutations are responsible for thrombocytopenia have been identified, and this also led to the recognition of several novel nosographic entities, such as thrombocytopenias deriving from mutations in CYCS, TUBB1, FLNA, ITGA2B/ITGB3, ANKRD26 and ACTN1. 23636669 2013
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 GeneticVariation phenotype BEFREE THC4 is an autosomal dominant mild thrombocytopenia described in only one large family from New Zealand and due to a mutation (G41S) of the somatic isoform of the cytochrome c (CYCS) gene. 24326104 2014
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 GeneticVariation phenotype BEFREE Megakaryocytes from CYCS mutation-associated thrombocytopenia release platelets by both proplatelet-dependent and -independent processes. 27861742 2017
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 GeneticVariation phenotype CLINVAR Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders. 31064749 2019
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 Biomarker phenotype CTD_human A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia. 18345000 2008
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 GeneticVariation phenotype LHGDN A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia. 18345000 2008
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 GeneticVariation phenotype LHGDN Absence of CYCS mutations in a large Italian cohort of patients with inherited thrombocytopenias of unknown origin. 19172527 2009
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 Biomarker phenotype HPO
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
0.650 Biomarker phenotype GENOMICS_ENGLAND A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia. 18345000 2008