Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.060 Biomarker phenotype BEFREE The greatest challenge in the care of chronic HCV patients with thrombocytopenia is the difficulty in initiating or maintaining IFN containing anti-viral therapy. 28293407 2017
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.060 Biomarker phenotype BEFREE Most frequent all grade IFN-α-related toxicities were asthenia (n = 10), lymphopenia (n = 7), thrombopenia (n = 6), and anemia (n = 5). 28748315 2017
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.060 GeneticVariation phenotype BEFREE RBV-induced anemia was independently correlated with SLC29A1 rs760370 AA genotype (OR, 2.90; 95% CI, 1.29-6.54, P = 0.010), and the severity of IFN-induced thrombocytopenia was related to GG genotype (OR, 4.98; 95% CI, 1.27-19.61; P = 0.021); the detected effects held true for HCV-2a patients but weakened in HCV-1b patients. 26750805 2016
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.060 Biomarker phenotype BEFREE However, PEG-IFNα-associated thrombocytopenia developed in 3 patients who carried the class II HLA allele DRB01*04. 24657484 2014
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.060 Biomarker phenotype BEFREE The latter functional SNP in ITPA locus was the most significant SNP associated with RBV-induced anemia as well as IFN-induced thrombocytopenia. 22156486 2011
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.060 Biomarker phenotype BEFREE The severe thrombocytopenia failed to resolve with cessation of the peg-IFN/ribaviron. 15682410 2005