Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.370 Biomarker phenotype BEFREE Only XN-2000 fluorescent, Sapphire optical, and CD61 methods are sufficiently accurate for making appropriate clinical decisions in patients with severe thrombocytopenia. 30222860 2018
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.370 GeneticVariation phenotype BEFREE In the last 5 years, nine new genes whose mutations are responsible for thrombocytopenia have been identified, and this also led to the recognition of several novel nosographic entities, such as thrombocytopenias deriving from mutations in CYCS, TUBB1, FLNA, ITGA2B/ITGB3, ANKRD26 and ACTN1. 23636669 2013
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.370 GeneticVariation phenotype BEFREE These findings suggest a model whereby the integrin β3-L718P mutation contributes to thrombocytopenia through gain-of-function mechanisms. 23253071 2013
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.370 GeneticVariation phenotype BEFREE We hypothesized that susceptibility to P. vivax-induced thrombocytopenia could be associated with polymorphisms on relevant platelet membrane integrins: integrin α2 (C807T), and integrin β3 (T1565C). 23249684 2013
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.370 GeneticVariation phenotype BEFREE We describe two Italian families with moderate thrombocytopenia with large platelets, defective platelet function and moderate/severe mucocutaneous bleeding, transmitted as an autosomal dominant trait and associated with a novel integrin beta(3)-gene (ITGB3) mutation. 19336737 2009
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.370 Biomarker phenotype LHGDN A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy. 16317099 2006
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.370 Biomarker phenotype CTD_human Ceftriaxone causes drug-induced immune thrombocytopenia and hemolytic anemia: characterization of targets on platelets and red blood cells. 15225244 2004
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
0.370 Biomarker phenotype LHGDN "A site involving the ""hybrid"" and PSI homology domains of GPIIIa (beta 3-integrin subunit) is a common target for antibodies associated with quinine-induced immune thrombocytopenia." 12393510 2003