Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.370 | Biomarker | phenotype | BEFREE | Only XN-2000 fluorescent, Sapphire optical, and CD61 methods are sufficiently accurate for making appropriate clinical decisions in patients with severe thrombocytopenia. | 30222860 | 2018 | ||||
|
0.370 | GeneticVariation | phenotype | BEFREE | In the last 5 years, nine new genes whose mutations are responsible for thrombocytopenia have been identified, and this also led to the recognition of several novel nosographic entities, such as thrombocytopenias deriving from mutations in CYCS, TUBB1, FLNA, ITGA2B/ITGB3, ANKRD26 and ACTN1. | 23636669 | 2013 | ||||
|
0.370 | GeneticVariation | phenotype | BEFREE | These findings suggest a model whereby the integrin β3-L718P mutation contributes to thrombocytopenia through gain-of-function mechanisms. | 23253071 | 2013 | ||||
|
0.370 | GeneticVariation | phenotype | BEFREE | We hypothesized that susceptibility to P. vivax-induced thrombocytopenia could be associated with polymorphisms on relevant platelet membrane integrins: integrin α2 (C807T), and integrin β3 (T1565C). | 23249684 | 2013 | ||||
|
0.370 | GeneticVariation | phenotype | BEFREE | We describe two Italian families with moderate thrombocytopenia with large platelets, defective platelet function and moderate/severe mucocutaneous bleeding, transmitted as an autosomal dominant trait and associated with a novel integrin beta(3)-gene (ITGB3) mutation. | 19336737 | 2009 | ||||
|
0.370 | Biomarker | phenotype | LHGDN | A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy. | 16317099 | 2006 | ||||
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0.370 | Biomarker | phenotype | CTD_human | Ceftriaxone causes drug-induced immune thrombocytopenia and hemolytic anemia: characterization of targets on platelets and red blood cells. | 15225244 | 2004 | ||||
|
0.370 | Biomarker | phenotype | LHGDN | "A site involving the ""hybrid"" and PSI homology domains of GPIIIa (beta 3-integrin subunit) is a common target for antibodies associated with quinine-induced immune thrombocytopenia." | 12393510 | 2003 |