Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype LHGDN Control of von Willebrand factor multimer size and implications for disease. 12163004 2002
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype LHGDN von Willebrand factor: two sides of a coin. 16102036 2005
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype CTD_human Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole. 22352330 2012
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype LHGDN Functional property of von Willebrand factor under flowing blood. 11843285 2002
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype LHGDN In this study we hypothesized that anthrax infection modulates the activity of von Willebrand factor (VWF) and its endogenous regulator ADAMTS13, which play important roles in hemostasis and thrombosis, including interaction of endothelial cells with platelets. 18263586 2008
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype CTD_human Altered von Willebrand factor molecule in children with thrombosis following asparaginase-prednisone-vincristine therapy for leukemia. 3875694 1985
Entrez Id: 79001
Gene Symbol: VKORC1
VKORC1 		0.300 Biomarker phenotype CTD_human Inhibition of VKORC1 by oral anticoagulants (OACs) is clinically used in therapy and in prevention of thrombosis. 29581108 2018
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker phenotype GENOMICS_ENGLAND Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension. 21454469 2011
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 AlteredExpression phenotype LHGDN Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. 14726398 2004
Entrez Id: 7408
Gene Symbol: VASP
VASP 		0.020 Biomarker phenotype LHGDN Impaired platelet responsiveness to clopidogrel identified by flow cytometric vasodilator-stimulated phosphoprotein (VASP) phosphorylation in patients with subacute stent thrombosis. 17938817 2007
Entrez Id: 7408
Gene Symbol: VASP
VASP 		0.020 PosttranslationalModification phenotype LHGDN The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis. 18064332 2007
Entrez Id: 7301
Gene Symbol: TYRO3
TYRO3 		0.300 Biomarker phenotype CTD_human Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses. 15733062 2005
Entrez Id: 81027
Gene Symbol: TUBB1
TUBB1 		0.010 GeneticVariation phenotype LHGDN The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure. 15956286 2005
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14 		0.010 Biomarker phenotype LHGDN Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis. 16186421 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 Biomarker phenotype CTD_human The study was performed to investigate, in an animal model of arterial thrombosis in vivo, whether diclofenac differentially influences platelet activation and thrombosis in vessels under non-stimulated conditions or during acute systemic inflammation, such as induced by tumor necrosis factor-alpha (TNF-alpha). 19691487 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 GeneticVariation phenotype LHGDN These data suggest that the TNF-alpha -308 A allele is associated with increased PTFE graft thrombosis and failure in hemodialysis patients. 12580317 2003
Entrez Id: 7056
Gene Symbol: THBD
THBD 		0.310 Biomarker phenotype LHGDN Soluble P-selectin and thrombomodulin-protein C-Protein S pathway in cyanotic congenital heart disease with secondary erythrocytosis. 14987915 2003
Entrez Id: 7056
Gene Symbol: THBD
THBD 		0.310 Biomarker phenotype CTD_human Although larger studies are required, this case report suggests that thrombomodulin gene mutations could be an additional genetic risk factor for thrombosis in carriers of the factor V Leiden mutation. 11132655 2000
Entrez Id: 7056
Gene Symbol: THBD
THBD 		0.310 Biomarker phenotype CTD_human Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis. 11518727 2001
Entrez Id: 7035
Gene Symbol: TFPI
TFPI 		0.020 AlteredExpression phenotype LHGDN Elevated TF and TFPI levels may be related to thrombosis and atherosclerosis in CRF patients on PD. 14610342 2003
Entrez Id: 7035
Gene Symbol: TFPI
TFPI 		0.020 AlteredExpression phenotype LHGDN We conclude that thrombosis patients with low levels of free TFPI are at an increased risk of recurrent VTE. 16270631 2005
Entrez Id: 6916
Gene Symbol: TBXAS1
TBXAS1 		0.200 Biomarker phenotype RGD The effect of ozagrel sodium on photochemical thrombosis in rat: therapeutic window and combined therapy with heparin sodium. 12384182 2002
Entrez Id: 6915
Gene Symbol: TBXA2R
TBXA2R 		0.010 Biomarker phenotype LHGDN Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. 12796499 2003
Entrez Id: 6573
Gene Symbol: SLC19A1
SLC19A1 		0.010 GeneticVariation phenotype LHGDN G80A reduced folate carrier SNP modulates cellular uptake of folate and affords protection against thrombosis via a non homocysteine related mechanism. 15964598 2005
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.300 Therapeutic phenotype CTD_human Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor. 25339356 2015