Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
0.100 Biomarker disease HPO
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
0.100 Biomarker disease HPO
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
0.100 Biomarker disease HPO
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.100 Biomarker disease HPO
Entrez Id: 1031
Gene Symbol: CDKN2C
CDKN2C
0.100 Biomarker disease HPO
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.030 Biomarker disease BEFREE A continuous cell line (YT cells) with inducible receptor for T cell growth factor (TCGF)/interleukin 2 (IL 2) was established from a 15-yr-old boy with acute lymphoblastic lymphoma and thymoma. 2578514 1985
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.050 Biomarker disease BEFREE The receptor for mouse interferon gamma (IFN-gamma) was purified from detergent-solubilized plasma membranes of EL-4, a thymoma cell line which expresses a high number of receptors on its cell surface. 2137461 1990
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5
0.010 Biomarker disease BEFREE In female MG patients, the DRw15-Dw2-positive haplotype T-2.1 was strongly correlated with the presence of thymoma (T-MG). 1973409 1990
Entrez Id: 1134
Gene Symbol: CHRNA1
CHRNA1
0.020 Biomarker disease BEFREE Neoplastic epithelial cells express alpha-subunit of muscle nicotinic acetylcholine receptor in thymomas from patients with myasthenia gravis. 1995332 1991
Entrez Id: 7273
Gene Symbol: TTN
TTN
0.050 AlteredExpression disease BEFREE Therefore, expressed titin from the MIR of the molecule is a sensitive marker antigen for evaluating the presence of thymoma in MG. 8351016 1993
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
0.040 GeneticVariation disease BEFREE The DRB1*1202 haplotype was associated with thymoma, older onset patients, ocular lesions, and mid to high anti-AchR titres. 8508049 1993
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
0.030 GeneticVariation disease BEFREE The DRB1*1202 haplotype was associated with thymoma, older onset patients, ocular lesions, and mid to high anti-AchR titres. 8508049 1993
Entrez Id: 7070
Gene Symbol: THY1
THY1
0.020 Biomarker disease BEFREE First, somatic cell hybridization analysis using Thy-1-deficient murine thymoma cell lines with known biochemical defects as fusion partners showed that the PNH cell lines belong to complementation class A, which is known not to synthesize N-acetylglucosaminyl-phosphatidylinositol. 8426120 1993
Entrez Id: 7070
Gene Symbol: THY1
THY1
0.020 Biomarker disease BEFREE While Mo-MuLV only induced Thy-1+ thymomas, v-abl- and BCR-ABL-induced thymomas often contained mixed populations of B220+ and Thy-1+ lymphocytes in the same tumor. 8396667 1993
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
0.010 Biomarker disease BEFREE While Mo-MuLV only induced Thy-1+ thymomas, v-abl- and BCR-ABL-induced thymomas often contained mixed populations of B220+ and Thy-1+ lymphocytes in the same tumor. 8396667 1993
Entrez Id: 25
Gene Symbol: ABL1
ABL1
0.010 Biomarker disease BEFREE While Mo-MuLV only induced Thy-1+ thymomas, v-abl- and BCR-ABL-induced thymomas often contained mixed populations of B220+ and Thy-1+ lymphocytes in the same tumor. 8396667 1993
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
0.040 GeneticVariation disease BEFREE In contrast, no obvious association of HLA-DQA1, DQB1, DRB1 and DPB1 alleles with either late-onset patients or patients with thymoma was observed. 7749041 1994
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.010 Biomarker disease BEFREE These results support the ectopic production of authentic PTH by a thymoma and indicate a novel tumoral cause of primary hyperparathyroidism. 8077382 1994
Entrez Id: 5281
Gene Symbol: PIGF
PIGF
0.010 AlteredExpression disease BEFREE For cloning PIG-F cDNA we chose a transient expression method and cotransfected a human T-cell cDNA library made with a vector bearing an origin of replication of polyoma virus with a plasmid bearing polyoma virus large T into the class F murine thymoma mutant. 8081220 1994
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
0.010 GeneticVariation disease BEFREE In contrast, no obvious association of HLA-DQA1, DQB1, DRB1 and DPB1 alleles with either late-onset patients or patients with thymoma was observed. 7749041 1994
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 Biomarker disease BEFREE There was significant difference in p53 protein immunopositivity between thymic carcinoma and each of the noninvasive or invasive/metastatic thymomas. 7572785 1995
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.010 AlteredExpression disease BEFREE Expression of bcl-2 protein was analysed in 30 cases of thymoma by immunohistological staining of paraffin-embedded tissue. 8522289 1995
Entrez Id: 4656
Gene Symbol: MYOG
MYOG
0.010 AlteredExpression disease BEFREE These results indicate that cells within the thymus and thymoma express AChR and its regulatory protein myogenin and that such cells, under certain conditions, might play a role in the triggering of myasthenia gravis. 7778671 1995
Entrez Id: 1674
Gene Symbol: DES
DES
0.010 Biomarker disease BEFREE By immunohistochemistry myoid cells (desmin and myoglobin positive) were present in all (four of four) thymuses studied and in two of five thymomas. 7778671 1995
Entrez Id: 4151
Gene Symbol: MB
MB
0.010 Biomarker disease BEFREE By immunohistochemistry myoid cells (desmin and myoglobin positive) were present in all (four of four) thymuses studied and in two of five thymomas. 7778671 1995