Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.310 Biomarker group CTD_human Enhancement of tongue carcinogenesis in Hras128 transgenic rats treated with 4-nitroquinoline 1-oxide. 20043093 2010
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.310 Biomarker group BEFREE An animal model for the rapid induction of tongue neoplasms in human c-Ha-ras proto-oncogene transgenic rats by 4-nitroquinoline 1-oxide: its potential use for preclinical chemoprevention studies. 16219633 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.300 Biomarker group CTD_human Early induction of cytokines/cytokine receptors and Cox2, and activation of NF-κB in 4-nitroquinoline 1-oxide-induced murine oral cancer model. 22561872 2012
Entrez Id: 360
Gene Symbol: AQP3
AQP3
0.300 Biomarker group CTD_human Critical role of aquaporin 3 on growth of human esophageal and oral squamous cell carcinoma. 21401805 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.300 Biomarker group CTD_human Deregulation of manganese superoxide dismutase (SOD2) expression and lymph node metastasis in tongue squamous cell carcinoma. 20618948 2010
Entrez Id: 1410
Gene Symbol: CRYAB
CRYAB
0.300 Biomarker group CTD_human Co-treating with arecoline and 4-nitroquinoline 1-oxide to establish a mouse model mimicking oral tumorigenesis. 19840781 2010
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
0.300 Biomarker group CTD_human Co-treating with arecoline and 4-nitroquinoline 1-oxide to establish a mouse model mimicking oral tumorigenesis. 19840781 2010
Entrez Id: 407007
Gene Symbol: MIR222
MIR222
0.300 Biomarker group CTD_human MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. 19487542 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.300 Biomarker group CTD_human Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice. 16543248 2006
Entrez Id: 3861
Gene Symbol: KRT14
KRT14
0.300 Biomarker group CTD_human Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice. 16543248 2006
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
0.300 Biomarker group CTD_human Intratumoural expression of thymidylate synthase is an independent predictor of prognosis in patients with squamous cell carcinoma of the tongue: results from a retrospective study. 16280240 2006
Entrez Id: 7012
Gene Symbol: TERC
TERC
0.300 Therapeutic group CTD_human Synergistic down-regulation of telomerase by all-trans retinoic acid and antisense oligonucleotide in oral squamous cell carcinoma cell line (Tca8113). 16051514 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.210 Biomarker group LHGDN Cytoplasmic localization of BAG-1 in leukoplakia and carcinoma of the tongue: correlation with p53 and c-erbB2 in carcinoma. 17549665 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.210 Biomarker group CTD_mouse Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice. 16543248 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.210 Biomarker group RGD Investigation of environmental factors for diagnosing malignant potential in oral epithelial dysplasia. 12167434 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.210 Biomarker group RGD p53 expression in various stages of 4-nitroquinoline 1-oxide induced carcinoma in the rat tongue. 9485768 1996
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.200 ModifyingMutation group RGD p16(CDKN2A) expression during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide. 18804414 2009
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.200 Biomarker group RGD Frequent mutation of p16(CDKN2A) exon 1 during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide. 17091472 2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.200 Biomarker group RGD Selective loss of resistant alleles at p15INK4B and p16INK4A genes in chemically-induced rat tongue cancers. 16527513 2006
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
0.200 Biomarker group RGD Selective loss of resistant alleles at p15INK4B and p16INK4A genes in chemically-induced rat tongue cancers. 16527513 2006
Entrez Id: 177
Gene Symbol: AGER
AGER
0.200 Therapeutic group RGD Expression of receptor for advanced glycation end products during rat tongue carcinogenesis by 4-nitroquinoline 1-oxide and effect of a selective cyclooxygenase-2 inhibitor, etodolac. 17374970 2006
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
0.200 Biomarker group RGD Expressions of junB and c-fos are enhanced in 4-nitroquinoline 1-oxide-induced rat tongue cancers. 14674993 2004
Entrez Id: 2353
Gene Symbol: FOS
FOS
0.200 Biomarker group RGD Expressions of junB and c-fos are enhanced in 4-nitroquinoline 1-oxide-induced rat tongue cancers. 14674993 2004
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.200 Biomarker group RGD Investigation of environmental factors for diagnosing malignant potential in oral epithelial dysplasia. 12167434 2002
Entrez Id: 6598
Gene Symbol: SMARCB1
SMARCB1
0.100 Biomarker group HPO