Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.140 Biomarker phenotype BEFREE Striatal DAT binding correlated with akinesia-rigidity (P < 0.001) but not with tremor; the metabolic PET imaging, nonspecific to the dopaminergic dysfunction, disclosed a set of brain regions correlating with the cardinal symptoms, including tremor. 29863572 2018
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.140 Biomarker phenotype BEFREE To enroll PD subjects as early as possible following diagnosis, subjects were eligible with only asymmetric bradykinesia or tremor plus a dopamine transporter (DAT) binding deficit on SPECT imaging. 30564614 2018
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.140 GeneticVariation phenotype BEFREE In this study, the correlation of neutrophil to lymphocyte ratio (NLR) as a marker of peripheral inflammation to striatal binding ratios (SBRs) of DAT SPECT images in bilateral caudate and putamen nuclei was calculated in 388 drug-naïve early PD patients [288 tremor dominant (TD), 73 postural instability and gait difficulty (PIGD), and 27 indeterminate] and 148 controls. 29713303 2018
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.140 Biomarker phenotype BEFREE Dopamine transporter imaging and several electrophysiological methods provide additional clues for tremor differential diagnosis. 28638597 2017
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.140 Biomarker phenotype HPO