Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.330 | GeneticVariation | disease | BEFREE | Association between HTR1B alleles and suicidal ideation in individuals with major depressive disorder. | 28007644 | 2017 | ||||
|
0.330 | Biomarker | disease | PSYGENET | In total, 14 single nucleotide polymorphisms (SNPs) in coding regions of 10 serotonergic genes (HTR1A, HTR1B, HTR1D, HTR2A, HTR3A, HTR3C, HTR3D, HTR3E, HTR5A and TPH2) were genotyped in 308 Chinese Han patients with major depressive disorder. | 21937687 | 2012 | ||||
|
0.330 | Biomarker | disease | PSYGENET | The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder. p11 is an S100 family member recently identified as a serotonin 1B [5-hydroxytryptamine 1B (5-HT(1B))] and serotonin 4 (5-HT(4)) receptor-binding protein. | 20962330 | 2010 | ||||
|
0.330 | Biomarker | disease | PSYGENET | The 5-HT1B receptor: a novel target for the pathophysiology of depression. | 19702551 | 2009 | ||||
|
0.330 | Biomarker | disease | PSYGENET | Our work indicated that the HTR1B gene might be involved in the development of suicidal ideation in MD among a Chinese Han population. | 19897250 | 2009 | ||||
|
0.330 | Biomarker | disease | BEFREE | Our work indicated that the HTR1B gene might be involved in the development of suicidal ideation in MD among a Chinese Han population. | 19897250 | 2009 | ||||
|
0.330 | Biomarker | disease | PSYGENET | Association study of serotonin 1B receptor (A-161T) genetic polymorphism and suicidal behaviors and response to fluoxetine in major depressive disorder. | 15365222 | 2004 | ||||
|
0.330 | GeneticVariation | disease | BEFREE | Substance abuse disorder and major depression are associated with the human 5-HT1B receptor gene (HTR1B) G861C polymorphism. | 12496953 | 2003 |