Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE Unsupervised hierarchical clustering demonstrated that patient variability is relatively dominant to the distinction of t(12;14) UL compared with non-t(12;14) UL or of t(12;14) UL compared with del(7q) UL. 22343407 2012
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 Biomarker group BEFREE These data suggest that t(12;14) breakpoints contribute to the pathogenesis of uterine leiomyoma by interrupting a complex regulation of HMGA2 and other genes embedded within and around it. 17045619 2006
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE Such similarity in chromosomal rearrangements suggests that there may be a pathogenetic relationship between IVL and uterine leiomyomata with t(12;14). 11904348 2002
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 Biomarker group BEFREE Shrinkage effect of gonadotropin releasing hormone agonist treatment on uterine leiomyomas and t(12;14). 11788889 2002
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas. 9892177 1999
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE hREC2, a RAD51-like gene, is disrupted by t(12;14) (q15;q24.1) in a uterine leiomyoma. 10565301 1999
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 Biomarker group BEFREE Using fluorescence in situ hybridization and radiation hybrid mapping, we map ESR2 within 14q23-24.1, to a region approximately 2 Mb centromeric to the t(12;14) breakpoint in uterine leiomyomata, between markers D14S63 and WI-7536. 9824210 1998
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE Three UL t(12;14) breakpoints have been localized within this contig, showing that a BCR of at least 400 kb exists on chromosome 14. 9740667 1998
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE Fluorescence in situ hybridization (FISH) analysis showed that this contig spanned the t(12;14) breakpoints in three uterine leiomyomas and that the breakpoints in these tumors occurred within a 1 Mb region. 9585056 1998
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE Our efforts have focused on cloning the t(12;14)(q14-q15;q23-q24) breakpoint in uterine leiomyoma to further our understanding of the biology of these tumors. 7601452 1995
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE Precise mapping of t(12;14) leiomyoma breakpoint on chromosome 14 between D14S298 and D14S540. 7585464 1995
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE As an initial step toward finding the gene or genes that are interrupted by the translocation breakpoint, a somatic cell hybrid carrying the derivative 14 as the single t(12;14) translocated chromosome was constructed from a leiomyoma cell line with this translocation. 7533530 1994
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE The finding in these leiomyosarcomas of rearrangements of the same regions of chromosomes 12 and 14 that are involved in the tumor-specific t(12;14)(q14-15;q23-24) of uterine leiomyoma indicates that the same genes in 12q and 14q might be important in the pathogenesis of benign and malignant smooth muscle tumors. 2397453 1990
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE The cytogenetic profiles of leiomyoma and lipoma are strikingly similar; both tumor types have nonrandom rearrangements of 12q13-15, t(12;14) in leiomyoma and t(3;12) in lipoma, as well as variant rearrangements of the same 12q segment. 2278965 1990
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 AlteredExpression group BEFREE The three previously identified cytogenetic subgroups were all represented in this series: del(7) (q21.2q31.2) was found in 11, trisomy 12 in five, and t(12;14)(q14-15;q23-24) in one leiomyoma. 2227952 1990
Entrez Id: 923
Gene Symbol: CD6
CD6
0.100 GeneticVariation group BEFREE A uterine leiomyoma showing both t(12;14) and del(7) abnormalities. 2702616 1989