|
HLA-DRB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Protective Role of HLA-DRB1*13:02 against Microscopic Polyangiitis and MPO-ANCA-Positive Vasculitides in a Japanese Population: A Case-Control Study.
|
27166610 |
2016 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of HLA-B*41:02 with Henoch-Schönlein Purpura (IgA Vasculitis) in Spanish individuals irrespective of the HLA-DRB1 status.
|
25889603 |
2015 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A validation study supported by the Vasculitis Clinical Research Consortium confirmed the strong association between the DRB1*15 allele and PR3-ANCA disease, among African Americans.
|
21617122 |
2011 |
|
HLA-DRB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Compared with normal controls, DRB1*1454 was significantly less prevalent in AASV patients (0/304 vs 14/400, p = 4.6 × 10(-4), p corrected (p(c)) = 0.017), whereas DRB1*1101 was significantly more frequent in patients with MPA (32/214 vs 26/400, p = 6.4 × 10(-4), p(c) = 0.023).
|
21354458 |
2011 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The association between HLA-C3 and vasculitis was not due to linkage disequilibrium with HLA-DRB1.
|
16947780 |
2006 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Analysis by SE genotype, however, demonstrated a striking relationship of vasculitis to 3 genotypes containing a double dose of the SE, specifically HLA-DRB1*0401/*0401 (OR 6.2, 95% CI 1.01-37.9), *0401/*0404 (OR 4.1, 95% CI 1.1-16.2), and *0101/*0401 (OR 4.0, 95% CI 1.4-11.6).
|
15529352 |
2004 |
|
HLA-DRB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
There was an association of HLA-DRB1*0901 with MPA and MPO-ANCA positive vasculitis in Japanese patients.
|
12858454 |
2003 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
To examine the HLA-DRB1 genotype of patients with cutaneous leukocytoclastic angiitis (CLA), a small-sized blood vessel vasculitis limited to skin, and determine if differences exist with Henoch-Schönlein purpura (HSP), a small-sized blood vessel vasculitis with cutaneous and systemic complications.
|
12022354 |
2002 |
|
HLA-DRB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
A slightly decreased representation of HLA-DRB1*13 and HLA-DQB1*0603 individuals was observed in our cohort of ANCA-associated systemic vasculitis (AASV) patients compared with controls.
|
10444278 |
1999 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Higher risk for vasculitis was observed in patients who carried 2 DRB1 susceptibility alleles, one characterized by the QKRAA sequence and the other by the QRRAA sequence (OR = 3).
|
9228123 |
1997 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A case-control study was designed to compare the frequency of the shared epitope, DRB1*04 alleles, DQA1, and DQB1 alleles of 31 patients with RV with that of 76 patients with rheumatoid arthritis (RA) without vasculitis.
|
9150071 |
1997 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Genetic variants at DRB1 (Dw subtypes), DQB, and C4 loci were compared in rheumatoid disease subjects with or without the extra-articular feature of Felty's syndrome or major vasculitis.
|
1991218 |
1991 |