| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | disease | BEFREE | The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis. | 31320177 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | Interleukin-6 (IL-6) is one of the key biomarkers and therapeutic target in systemic vasculitis. | 31780858 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Furthermore, serum CTRP1 levels were positively correlated with the time point of intravenous immunoglobulin (IVIG), WBC, N%, TNF-α, IL-1β, and IL-6 levels in the KD-CAL group.ConclusionCTRP1 may participate in the process of vasculitis and blood coagulation during the acute phase of KD. | 29360808 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | FIRS was defined based on the umbilical cord blood IL-6 concentration and the presence of funisitis and/or chorionic plate vasculitis.ResultsWomen with both MIAC and IAI had the highest median umbilical cord blood IL-6 concentrations and highest rates of FIRS. | 29186106 | 2018 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | IL-1 gene cluster, IL-6 and TNF-α polymorphisms have shown significant associations with some vasculitides. | 27455075 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | The findings in this case indicate that overproduction of IL-6 contributes to IgA vasculitis (Henoch-Schönlein purpura) as well as to the pathogenesis of CD. | 28168662 | 2017 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The aim of this study was to determine whether the genetic variant -174 IL-6 contributes to differences in the response to rituximab in patients with systemic autoimmune diseases, including systemic lupus erythematosus (SLE), inflammatory myopathies, anti-neutrophil cytoplasmic antibody-mediated vasculitis, systemic sclerosis, Sjöegren's syndrome, rheumatoid arthritis, and autoimmune hemolytic anemia. | 22734797 | 2012 |