×
Entrez Id:
6469
Gene Symbol:
SHH
SHH
0.300
Biomarker
disease
CTD_human
Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model.
27585885
2016
×
Entrez Id:
2736
Gene Symbol:
GLI2
GLI2
0.300
Biomarker
disease
CTD_human
Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model.
27585885
2016
×
Entrez Id:
4838
Gene Symbol:
NODAL
NODAL
0.300
Biomarker
disease
CTD_human
NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos.
23264560
2013
×
Entrez Id:
6469
Gene Symbol:
SHH
SHH
0.300
Biomarker
disease
CTD_human
NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos.
23264560
2013
×
Entrez Id:
2619
Gene Symbol:
GAS1
GAS1
0.300
Biomarker
disease
CTD_human
Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.
17525797
2007
×
Entrez Id:
6469
Gene Symbol:
SHH
SHH
0.300
Biomarker
disease
CTD_human
Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.
17525797
2007
×
Entrez Id:
7050
Gene Symbol:
TGIF1
TGIF1
0.300
Biomarker
disease
CTD_human
Embryonic fibroblasts from mice lacking Tgif were defective in cell cycling.
16705179
2006
×
Entrez Id:
6469
Gene Symbol:
SHH
SHH
0.300
Biomarker
disease
CTD_human
Wide phenotypic variability in families with holoprosencephaly and a sonic hedgehog mutation.
15107988
2004
×
Entrez Id:
57045
Gene Symbol:
TWSG1
TWSG1
0.300
Biomarker
disease
CTD_human
The mammalian twisted gastrulation gene functions in foregut and craniofacial development.
15013800
2004
×
Entrez Id:
6997
Gene Symbol:
TDGF1
TDGF1
0.300
Biomarker
disease
CTD_human
A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects.
12073012
2002
×
Entrez Id:
6496
Gene Symbol:
SIX3
SIX3
0.300
Biomarker
disease
CTD_human
Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly.
10369266
1999
×
Entrez Id:
2737
Gene Symbol:
GLI3
GLI3
0.110
GeneticVariation
disease
BEFREE
Meanwhile, it was speculated that the Gli3 gene, mutation of which is responsible for the arhinencephaly in Pdn/Pdn mice, might play a role in mesenchymal programmed cell death during development.
8711131
1995
×
Entrez Id:
2737
Gene Symbol:
GLI3
GLI3
0.110
Biomarker
disease
HPO
RNASEH2A
0.100
Biomarker
disease
HPO
×
Entrez Id:
9632
Gene Symbol:
SEC24C
SEC24C
0.100
Biomarker
disease
HPO
×
Entrez Id:
64093
Gene Symbol:
SMOC1
SMOC1
0.100
Biomarker
disease
HPO
RNASEH2B
0.100
Biomarker
disease
HPO
×
Entrez Id:
11277
Gene Symbol:
TREX1
TREX1
0.100
Biomarker
disease
HPO
×
Entrez Id:
6239
Gene Symbol:
RREB1
RREB1
0.100
Biomarker
disease
HPO
×
Entrez Id:
374654
Gene Symbol:
KIF7
KIF7
0.100
Biomarker
disease
HPO
×
Entrez Id:
219844
Gene Symbol:
HYLS1
HYLS1
0.100
Biomarker
disease
HPO
×
Entrez Id:
7353
Gene Symbol:
UFD1
UFD1
0.100
Biomarker
disease
HPO
RNASEH2C
0.100
Biomarker
disease
HPO
×
Entrez Id:
103
Gene Symbol:
ADAR
ADAR
0.100
Biomarker
disease
HPO
×
Entrez Id:
2187
Gene Symbol:
FANCB
FANCB
0.100
Biomarker
disease
HPO