|
LOC102723407
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
High levels of clonal IGHV SHM (SHM<sup>high</sup>) were associated with prolonged overall survival in DLBCL patients, particularly those without BCL2 or MYC translocation.
|
31640780 |
2019 |
|
LOC102723407
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
VH gene selection and mutational status in 52 cBCL, including 29 diffuse large B-cell lymphomas (cDLBCL, the most common subtype of cBCL), were analyzed by comparison with the 80 published canine germline VH gene sequences.
|
24332568 |
2014 |
|
LOC102723407
|
0.090 |
Biomarker
|
disease |
BEFREE |
NOTCH1 mutation increased the risk of transformation to diffuse large B-cell lymphoma independently from IGHV, with this being validated in resampling tests of replicability.
|
23295735 |
2013 |
|
LOC102723407
|
0.090 |
Biomarker
|
disease |
BEFREE |
IGHV gene repertoire is remarkably biased, implying an antigen-driven origin in DLBCL.
|
22982190 |
2012 |
|
LOC102723407
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
We analysed the nucleotide sequence of clonal IgV heavy-chain gene (IgVH) rearrangements in 51 cases of PCBCL (25 follicle centre, 19 marginal zone and seven diffuse large B-cell lymphoma, leg-type) and compared IgVH sequences with their closest germline segment in the GenBank database.
|
19906071 |
2010 |
|
LOC102723407
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Somatically mutated immunoglobulin IGHV@ genes without intraclonal heterogeneity indicate a postgerminal centre origin of primary intraocular diffuse large B-cell lymphomas.
|
17760806 |
2007 |
|
LOC102723407
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Additionally, analysis of somatic mutations of the immunoglobulin heavy chain variable region (IgVH) genes were performed in CD5(+) DLBLs.
|
12393524 |
2003 |
|
LOC102723407
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Comparative studies of somatic and ongoing mutations in immunoglobulin heavy-chain variable region genes in diffuse large B-cell lymphomas of the stomach and the small intestine.
|
14567725 |
2003 |
|
LOC102723407
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
To clarify the origin and cellular characteristics of CD10-positive DLBCL, we analyzed 36 de novo cases of DLBCL for somatic mutations of the immunoglobulin heavy chain variable region (VH) genes and for their immunophenotypes.
|
12406188 |
2002 |