Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
0.350 AlteredExpression disease BEFREE Inhibition of SYK in DLBCL cells with tonic BCR signaling decreased phospho-AKT and phospho-FOXO1 levels and triggered FOXO1-driven gene expression. 26585955 2016
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
0.350 Biomarker disease BEFREE We also demonstrate that FOXO1 knockdown in cells with silenced TXN expression markedly reduces ROS-induced apoptosis, indicating that FOXO1 is the major sensor and effector of oxidative stress in OxPhos-DLBCLs. 27132507 2016
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
0.350 AlteredExpression disease BEFREE Reporter-gene assay showed that miR-21 directly targeted and suppressed the FOXO1 expression, and subsequently inhibited Bim transcription in DLBCL cells. 25909227 2015
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
0.350 GeneticVariation disease BEFREE The independent relationship of mutations in FOXO1 to survival, transcending the prognostic influence of the R-IPI and COO, indicates that FOXO1 mutation is a novel prognostic factor that plays an important role in DLBCL pathogenesis. 23460611 2013
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
0.350 AlteredExpression disease BEFREE We show that FOXO1 is highly expressed in normal germinal center B cells as well as in non-Hodgkin lymphomas, including follicular lymphoma, diffuse large B-cell lymphoma, mucosa-associated lymphoid tissue non-Hodgkin lymphoma, B-cell chronic lymphocytic leukemia, and mantle cell lymphoma. 22343918 2012
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
0.350 CausalMutation disease CGI