Gene: MCM8 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 84515
Gene Symbol: MCM8
MCM8 		0.340 AlteredExpression disease BEFREE Our objective was to characterize MCM 8 and 9 gene expression in the menstrual cycle, and to compare MCM 8/9 expression in POI vs normo-ovulatory women. 30276597 2019
Entrez Id: 84515
Gene Symbol: MCM8
MCM8 		0.340 GeneticVariation disease BEFREE Mutations in MCM8/9 correlate principally with primary ovarian failure/insufficiency (POF/POI) and infertility indicating a meiotic defect. 30743181 2019
Entrez Id: 84515
Gene Symbol: MCM8
MCM8 		0.340 Biomarker disease BEFREE MCM8 was sequenced in 155 POI participants, whereas MCM9 was sequenced in 151 participants. 27802094 2017
Entrez Id: 84515
Gene Symbol: MCM8
MCM8 		0.340 GeneticVariation disease BEFREE Our result suggests novel mutations p. H317L and p. H601R in the MCM8 gene are potentially causative for POI by dysfunctional DNA repair. 27573988 2016
Entrez Id: 84515
Gene Symbol: MCM8
MCM8 		0.340 Biomarker disease GENOMICS_ENGLAND MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination. 22771120 2012