Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
0.030 Biomarker disease BEFREE Notch2, but not Notch1, plays indispensable roles in kidney organogenesis, and Notch2 haploinsufficiency is associated with Alagille syndrome. 23806616 2013
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
0.030 Biomarker disease BEFREE Deletion of Notch1 from the CNC using Wnt1-cre; Notch1 F/F mice did not recapitulate the midface hypoplasia of Alagille syndrome. 22156581 2012
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
0.030 GeneticVariation disease BEFREE Three human disorders including a neoplasia (a T-cell acute lymphoblastic leukemia/lymphoma), a late onset neurological disease (CADASIL) and a developmental disorder (the Alagille syndrome) are associated with mutations in, respectively, the Notch1, Notch3 and Jagged1 genes, pointing out the broad spectrum of Notch activity in humans. 10075489 1998