Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
0.900 GeneticVariation disease BEFREE The major site for mutations leading to autosomal dominant polycystic kidney disease (ADPKD) is at the PKD1 locus, previously mapped to 16p13. 2339691 1990
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
0.900 GeneticVariation disease BEFREE Linkage study of a large family with autosomal dominant polycystic kidney disease with reduced expression. Absence of linkage to the PKD 1 locus. 2370053 1990
Entrez Id: 5587
Gene Symbol: PRKD1
PRKD1
0.100 GeneticVariation disease BEFREE Linkage study of a large family with autosomal dominant polycystic kidney disease with reduced expression. Absence of linkage to the PKD 1 locus. 2370053 1990
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE The major diseases mapped to chromosome 16 are adult polycystic kidney disease and those resulting from mutations in the alpha globin complex. 2443701 1987
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
0.100 GeneticVariation disease BEFREE The major diseases mapped to chromosome 16 are adult polycystic kidney disease and those resulting from mutations in the alpha globin complex. 2443701 1987
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
0.100 GeneticVariation disease BEFREE Adult polycystic kidney disease and linked RFLPs at the alpha globin locus: a genetic study in the South Wales population. 2443703 1987
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Adult polycystic kidney disease and linked RFLPs at the alpha globin locus: a genetic study in the South Wales population. 2443703 1987
Entrez Id: 1950
Gene Symbol: EGF
EGF
0.060 Biomarker disease BEFREE In contrast to NK cells, the growth and propagation of ADPKD cells were not supported by defined medium alone but required serum supplementation and ADPKD cells did not respond to growth factors (insulin, transferrin, EGF) that promoted the growth of NK cells. 2475661 1989
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
0.900 GeneticVariation disease BEFREE The adult polycystic kidney disease locus (PKD1) has also been assigned to 16p13. 2570019 1989
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
0.900 GeneticVariation disease BEFREE Linkage studies have been carried out using two probes (3'HVR and 24-1) linked to ADPKD on locus PKD1 and two probes (alpha 1-PstI and BamH-I/EcoRI-zeta 2 fragment) allowing detection of alpha-thalassemia with either a 3.7-kb deletion or a 4.2-kb deletion. 2767679 1989
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
0.100 GeneticVariation disease BEFREE Our results show that to avoid misinterpretation it is important to investigate the occurrence of an alpha-gene deletion when polymorphisms situated in the alpha-globin locus are used for linkage studies on ADPKD. 2767679 1989
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Our results show that to avoid misinterpretation it is important to investigate the occurrence of an alpha-gene deletion when polymorphisms situated in the alpha-globin locus are used for linkage studies on ADPKD. 2767679 1989
Entrez Id: 2056
Gene Symbol: EPO
EPO
0.020 Biomarker disease BEFREE Erythropoietin (EPO) formation in kidneys of 18 patients with autosomal dominant polycystic kidney disease (ADPKD) was investigated. 2794053 1989
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
0.100 GeneticVariation disease BEFREE The results show that APKD is closely linked to the PGP locus on the short arm of chromosome 16 (16p13----p12), which is consistent with the previously reported linkage both to PGP and to the alpha globin locus. 2821260 1987
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE The results show that APKD is closely linked to the PGP locus on the short arm of chromosome 16 (16p13----p12), which is consistent with the previously reported linkage both to PGP and to the alpha globin locus. 2821260 1987
Entrez Id: 283871
Gene Symbol: PGP
PGP
0.040 Biomarker disease BEFREE The genetic distance between PGP and APKD shows a maximum likelihood value of the recombination fraction at zero with a lod score of 5 X 5. 2821260 1987
Entrez Id: 3240
Gene Symbol: HP
HP
0.010 Biomarker disease BEFREE There is no evidence of linkage between APKD and either GPT or HP. 2821260 1987
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
0.100 GeneticVariation disease BEFREE Hitherto, mutations that lead to autosomal dominant adult-type polycystic kidney disease have been found to be linked to the alpha-globin genes on the short arm of chromosome 16. 2898665 1988
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Hitherto, mutations that lead to autosomal dominant adult-type polycystic kidney disease have been found to be linked to the alpha-globin genes on the short arm of chromosome 16. 2898665 1988
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
0.900 GeneticVariation disease BEFREE The localization of the autosomal dominant polycystic kidney disease locus (PKD1) within an array of anonymous polymorphic DNA sequences on chromosome 16 band p13 was determined by multipoint mapping. 2906325 1988
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE In these families, linkage analysis was carried out with a cloned DNA sequence from the alpha-globin locus known to be closely linked to the disease gene in adult onset ADPKD. 2924430 1989
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
0.100 GeneticVariation disease BEFREE In these families, linkage analysis was carried out with a cloned DNA sequence from the alpha-globin locus known to be closely linked to the disease gene in adult onset ADPKD. 2924430 1989
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
0.100 GeneticVariation disease BEFREE Hence we have searched for a linkage marker for APCKD; we show here that the APCKD locus is closely linked to the alpha-globin locus on the short arm of chromosome 16 (zeta = 25.85, theta = 0.05). 2995836 1985
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Hence we have searched for a linkage marker for APCKD; we show here that the APCKD locus is closely linked to the alpha-globin locus on the short arm of chromosome 16 (zeta = 25.85, theta = 0.05). 2995836 1985
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Further study showed that the phosphoglycolate phosphatase locus is also closely linked to both the locus for adult polycystic kidney disease and the alpha globin gene cluster. 3008903 1986