Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE We have compared the clinical features of ADPKD caused by mutations at the PKD1 locus (linked to the alpha-globin complex on chromosome 16) with those of disease not linked to the locus (non-PKD1). 1360045 1992
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Autosomal dominant polycystic kidney disease (PKD1) is linked to the alpha-globin locus near the telomere of chromosome 16p. 1349580 1992
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE In these families, linkage analysis was carried out with a cloned DNA sequence from the alpha-globin locus known to be closely linked to the disease gene in adult onset ADPKD. 2924430 1989
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Our results show that to avoid misinterpretation it is important to investigate the occurrence of an alpha-gene deletion when polymorphisms situated in the alpha-globin locus are used for linkage studies on ADPKD. 2767679 1989
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Hitherto, mutations that lead to autosomal dominant adult-type polycystic kidney disease have been found to be linked to the alpha-globin genes on the short arm of chromosome 16. 2898665 1988
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE No evidence was found to suggest heterogeneity of genetic linkage between alpha-globin and the APKD locus in this population. 3610154 1987
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE The results show that APKD is closely linked to the PGP locus on the short arm of chromosome 16 (16p13----p12), which is consistent with the previously reported linkage both to PGP and to the alpha globin locus. 2821260 1987
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE The major diseases mapped to chromosome 16 are adult polycystic kidney disease and those resulting from mutations in the alpha globin complex. 2443701 1987
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Adult polycystic kidney disease and linked RFLPs at the alpha globin locus: a genetic study in the South Wales population. 2443703 1987
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Further study showed that the phosphoglycolate phosphatase locus is also closely linked to both the locus for adult polycystic kidney disease and the alpha globin gene cluster. 3008903 1986
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
0.100 GeneticVariation disease BEFREE Hence we have searched for a linkage marker for APCKD; we show here that the APCKD locus is closely linked to the alpha-globin locus on the short arm of chromosome 16 (zeta = 25.85, theta = 0.05). 2995836 1985